From: Italian guidelines for the prevention and management of dental trauma in children
I | Evidence from several randomised controlled clinical trials, systematic reviews of randomised trials and/or international guidelines |
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II | Evidence from one adequately designed randomised clinical trial |
III | Evidence from non-randomised cohort studies with concurrent or historical controls, or meta-analyses including this type of studies |
IV | Evidence from retrospective case-controlled studies, or meta-analyses including this type of studies |
V | Evidence from case series with no control group |
VI | Evidence based on the opinion of recognised experts or expert panels, as indicated in guidelines or consensus conferences, based on the opinion of the panel. |