Table 1 Demographic data and measured biomarkers in T1DM patients and controls

Gender (boys/girls)

41/30

26/24

0.580^a

age (years)

13 (11–16)

12 (10–13.2)

0.071^b

Duration of diabetes (years)

5 (4–8)

–

–

HbA1c (%)

7.5 (6.8–8.2)

5.3 (5.1–5.3)

< 0.001**^b

Glu (mg/dl)

203 ± 73

86 ± 9

< 0.001**^c

Ca (mg/dl)

9.75 ± 0.38

9.62 ± 0.36

0.066^c

P (mg/dl)

4.39 ± 0.52

4.42 ± 0.9

0.862^c

Mg (mg/dl)

1.92 (1.76–2.04)

1.95 (1.8–2.09)

0.105^b

ALP (U/L)

222 ± 110

151 ± 82

< 0.001**^c

PTH (pg/ml)

46.75 ± 17.1

26.56 ± 9.87

< 0.001**^c

25(OH) D (ng/ml)

26.6 (21.8–32.3)

54.3 (48.7–60.5)

< 0.001**^b

SGOT (U/L)

19 (15–24)

21 (17–27)

0.092^b

SGPT (U/L)

15 (12–19)

14 (12–18)

0.514^b

ACR ratio

3.35 (2.47–5.97)

–

–

OPG (pg/ml)

314 (171–504)

392 (271–667)

0.025*^b

RANKL (pg/ml)

545 (107–3377)

234 (12–2046)

0.037*^b

RANK (pg/ml)

43 (18–110)

52 (18–91)

0.946^b

RANKL/OPG

1.7 (0.41–7.22)

0.64 (0.02–2.95)

0.002*^b