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Table 7 Reactions occurring during DPTs with corresponding times and dose reactions

From: Epidemiology and drug allergy results in children investigated in allergy unit of a tertiary-care paediatric hospital setting

Drug Categories

IRs

NO.

TI (m)

Dose

Non- IRs

NO.

TI (h-d)

Dose

BLs (20)

Ana

1 (5%)

90

7/10

MPE

5 (25%)

4:6–8 h/ 2d

100%

U

4 (20%)

< 60

7/10

1: 6 h/ 3d

ER

1 (5%)

< 60

7/10

U

4 (20%)

2:6-8 h/4d

1: 6–8 h/1d

1a

1:7/10

3:100%

    

ER

3 (15%)

6–12 h/2d

100%

    

ER+ Diarrhea

1 (5%)

6 h/3d

100%

    

ED

1 (5%)

8–10 h/1d

7/10

Macrolides (3)

U

2 (66.7%)

< 60

1/10

7/10

ER + Diarrhea

1 (33.3%)

30

7/10

NSAIDs (11)

A

4 (36.3%)

< 60

7/10

A

2 (18.2%)

> 1 h/1d

7/10

UA

2 (18.2%)

< 60

1/10

7/10

U

2 (18.2%)

< 60

7/10

ER

1 (9.1%)

< 60

7/10

Local anesthetics (1)

MPE

1 (100%)

10

2 ml

  1. 1/10–2/10–7/10: fractioned dose on first day of DPT
  2. TI time interval
  3. m minutes
  4. d days of drugs administration
  5. h hours from the last dose
  6. A Angioedema, ER Erythematous Rash, U Urticaria, MPE Maculopapular exanthema, UA Urticaria+ Angioedema, Ana anaphylaxis, ED exfoliative dermatitis
  7. a72 h after discontinuation (similar to a history of reactions)