Skip to main content

Table 7 Reactions occurring during DPTs with corresponding times and dose reactions

From: Epidemiology and drug allergy results in children investigated in allergy unit of a tertiary-care paediatric hospital setting

Drug CategoriesIRsNO.TI (m)DoseNon- IRsNO.TI (h-d)Dose
BLs (20)Ana1 (5%)907/10MPE5 (25%)4:6–8 h/ 2d100%
U4 (20%)< 607/101: 6 h/ 3d
ER1 (5%)< 607/10U4 (20%)2:6-8 h/4d
1: 6–8 h/1d
1a
1:7/10
3:100%
    ER3 (15%)6–12 h/2d100%
    ER+ Diarrhea1 (5%)6 h/3d100%
    ED1 (5%)8–10 h/1d7/10
Macrolides (3)U2 (66.7%)< 601/10
7/10
ER + Diarrhea1 (33.3%)307/10
NSAIDs (11)A4 (36.3%)< 607/10A2 (18.2%)> 1 h/1d7/10
UA2 (18.2%)< 601/10
7/10
U2 (18.2%)< 607/10
ER1 (9.1%)< 607/10
Local anesthetics (1)MPE1 (100%)102 ml
  1. 1/10–2/10–7/10: fractioned dose on first day of DPT
  2. TI time interval
  3. m minutes
  4. d days of drugs administration
  5. h hours from the last dose
  6. A Angioedema, ER Erythematous Rash, U Urticaria, MPE Maculopapular exanthema, UA Urticaria+ Angioedema, Ana anaphylaxis, ED exfoliative dermatitis
  7. a72 h after discontinuation (similar to a history of reactions)