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Table 1 Major findings

From: Does virtual reality reduce pain in pediatric patients? A systematic review

ID

Title

First author

Publication year

Country

Sample size

Age

Study design

Virtual reality pattern

VR application

1

Virtual reality as complementary pain therapy in hospitalized patients with sickle cell disease

Agrawal A.K.

2019

United States

31

13–20

Feasibility study

Oculus Rift VR headset

VR was used to manage pain of vaso-occlusive pain episodes (VOE) in patients with sickle cell disease (SCD).

2

Effectiveness of audio visual distraction using virtual reality eyeglasses versus tablet device in child behavioral management during inferior alveolar nerve block

Al-Halabi M.N.

2018

Syria

102

6–10

Randomized Controlled Trial

Virtual reality box (VR Box)

VR was used to reduce pain in children behavioral management during inferior alveolar nerve block.

3

Effect of virtual reality headset for pediatric fear and pain distraction during immunization

Chad R.

2018

United States

34 (17 children and 17 parents)

Children: 6–17

Parents: 32–46

Pilot study

VR Headset

VR was used to reduce pain and fear during immunization.

4

Virtual Reality for Pediatric Needle Procedural Pain: Two Randomized Clinical Trials

Chan E.

2019

Australia

252

4–11

Randomized Controlled Trial

Google Pixel XL/Google Daydream

VR was used to reduce the pain during needle-related procedures, in 2 environments: emergency department and outpatient pathology.

5

A Randomized Controlled Trial of the Use of Virtual Reality for Needle-Related Procedures in Children and Adolescents in the Emergency Department

Dumoulin S.

2019

Canada

59

8–17

Randomized Controlled Trial

eMagin z800 HMD

VR was used to reduce the pain during needle-related procedures.

6

Effects of distraction using virtual reality technology on pain perception and anxiety levels in children during pulp therapy of primary molars

Niharika P.

2018

India

40

4–8

Randomized Controlled Trial

Google VR Box and Anti-Tank Virtual Reality 3D Glasses

VR was used to reduce pain during pulp therapy in pediatric patients.

7

Effects of Virtual Reality and External Cold and Vibration on Pain in 7- to 12-Year-Old Children During Phlebotomy: A Randomized Controlled Trial

Gerçeker G.Ö.

2018

United States

121

7–12

Randomized Controlled Trial

Samsung Gear Oculus headset

VR was used to reduce pain during phlebotomy.

8

The Effect of Virtual Reality Distraction on Pain Relief During Dressing Changes in Children with Chronic Wounds on Lower Limbs

Hua Y.

2015

China

65

4–16

Prospective randomized study

Head-mount display

VR was used to reduce pain resulted from dressing changes in pediatric patients with Chronic Wounds on Lower Limbs.

9

Effect of virtual reality on adolescent pain during burn wound care

Jeffs D.

2014

United States

30

10–17

Randomized Controlled Trial

Tripod-arm device

VR was used to reduce procedural pain during burn wound care.