Table 2 Clinical characteristics of present patients
From: Neonatal ten-year retrospective study on neural tube defects in a second level University Hospital
PRENATAL DIAGNOSIS | 2/7 newborns • 1 lumbosacral myelomeningocele • 1 terminal myelocystocele |
GESTATIONAL AGE | • 6 at term • 1 preterm (35 WG) |
TYPE OF DELIVERY | • 4 vaginal (1 precipitous) • 3 cesarean section |
TYPE OF NEURAL TUBE DEFECT | • 3 open: MMC, 2 lumbosacral, one of which associated with extradural lipoma, and 1 sacral • 4 closed: 2 occipital meningocele, 1 filar lipoma associated with dermal sinus, 1 terminal myelocystocele |
ASSOCIATED ANOMALIES AND/OR COMORBIDITIES | 3/7 newborns • 1 cerebellar and corpus callosum hypoplasia and feet deformities, with normal a-CGH findings • 1 hypospadias • 1 HIV infection, severe perinatal asphyxia, and congenital microcephaly (< −2SD) |
MEDICAL IMAGING/SPECIALISTIC EVALUATIONS | • 7/7 US of brain, skin and soft tissues over the spine, abdomen and heart • 1/7 lumbosacral X-ray • 1/7 CT of the head • 1/7 brain and spine MRI • 2/7 ophthalmological evaluation |
SURGICAL PROCEDURE | 5/7 newborns • 3 MMC • 2 meningocele |
POSTOPERATIVE EVOLUTION | • 4/5 uneventful • 1/5 surgical wound dehiscence |
NEURODEVELOPMENTAL OUTCOMES | • 3 normal neurodevelopmental profile and/or normal lower limbs motility and fecal continence • 2 severe neurological impairment • 1 global developmental delay • 1 reduced motility of lower limbs and fecal incontinence |