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Table 2 Clinical characteristics of present patients

From: Neonatal ten-year retrospective study on neural tube defects in a second level University Hospital

PRENATAL DIAGNOSIS2/7 newborns
• 1 lumbosacral myelomeningocele
• 1 terminal myelocystocele
GESTATIONAL AGE• 6 at term
• 1 preterm (35 WG)
TYPE OF DELIVERY• 4 vaginal (1 precipitous)
• 3 cesarean section
TYPE OF NEURAL TUBE DEFECT• 3 open: MMC, 2 lumbosacral, one of which associated with extradural lipoma, and 1 sacral
• 4 closed: 2 occipital meningocele, 1 filar lipoma associated with dermal sinus, 1 terminal myelocystocele
ASSOCIATED ANOMALIES AND/OR COMORBIDITIES3/7 newborns
• 1 cerebellar and corpus callosum hypoplasia and feet deformities, with normal a-CGH findings
• 1 hypospadias
• 1 HIV infection, severe perinatal asphyxia, and congenital microcephaly (< −2SD)
MEDICAL IMAGING/SPECIALISTIC EVALUATIONS• 7/7 US of brain, skin and soft tissues over the spine, abdomen and heart
• 1/7 lumbosacral X-ray
1/7 CT of the head
1/7 brain and spine MRI
2/7 ophthalmological evaluation
SURGICAL PROCEDURE5/7 newborns
• 3 MMC
• 2 meningocele
POSTOPERATIVE EVOLUTION• 4/5 uneventful
• 1/5 surgical wound dehiscence
NEURODEVELOPMENTAL OUTCOMES• 3 normal neurodevelopmental profile and/or normal lower limbs motility and fecal continence
• 2 severe neurological impairment
• 1 global developmental delay
• 1 reduced motility of lower limbs and fecal incontinence