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Table 1 Plasma and CSF levels of linezolid at different time points

From: Staphylococcal meningitis therapy with linezolid in a young infant: efficacy, CSF levels and side effects

Linezolid concentration (μg/ml)a
Time points Plasma CSF CSF/Plasma ratiob
1 h before the infusion 7.93 5.57 0.70
1 h after 48.44 4.91 0.10
6 h after 11.25 4.88 0.43
  1. aEffective range in infants: Cmax 6.8–36.7 μg/ml (ref. [6])
  2. bCSF/Plasma ratio describing a good penetration into CSF: 0.7–0.8+/− 0.3 (ref. [9])
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