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Table 3 Summary of the studies reporting the effects of different probiotics strains for the treatment of Irritable Bowel Syndrome and Functional Abdominal Pain-Not Otherwise

From: Probiotics’ efficacy in paediatric diseases: which is the evidence? A critical review on behalf of the Italian Society of Pediatrics

Author and year Intervention Control Treatment duration Follow up
Bauserman M et al. 2005 [107] Lactobacillus GG
1010 bacteria twice per day
Placebo
(inulin)
6 weeks No follow up after treatment period
Francavilla R et al. 2010 [108] Lactobacillus GG
3X109 CFU twice per day
Placebo 8 weeks 8 weeks
Guandalini S et al. 2010 [109] VSL#3
1 sachet once per day 4-11 years
Twice per day 12–18 years
Placebo 6 weeks 6 weeks a
Giannetti e et al. 2017 [110] Bifidobaacterium longum BB536 3 billions, Bifidobacterium infantis M-63 1 billion, Bifidobacterium breve M-16 V 1 billion Placebo 6 weeks 6 weeks a
Gawrońska A et al. 2007 [112] Lactobacillus GG
3X109 twice per day
Placebo 4 weeks No follow up after treatment period
Kianifar H et al
2015 [113]
Lactobacillus GG 1X1010 CFU/ml twice per day Placebo 4 weeks No follow up
after treatment period
  1. a At the completion of the 6 weeks, no preparation was administered for 2 weeks. Then each patient was switched to the other group and followed for 6 weeks