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Table 1 The demographic characteristics of all children

From: Platelet concentrate and type II IL-1 receptor are risk factors for allergic transfusion reactions in children

Variable

Number of patients/transfusion

Number of ATRs

P

Sex

n = 20,230

n = 117

0.514

-Female

9161

49 (0.53%)

 

-Male

11,069

68 (0.62%)

 

Age

n = 20,230

n = 117

< 0.0001

- < 3 years

9332

18 (0.19%)

 

-3-6 years

8350

55 (0.66%)

 

-6 − 12 years

1364

29 (2.13%)

 

−12-18 years

1184

15 (1.27%)

 

Allergic history

n = 20,230

n = 117

0.134

-None

18,395

102 (0.55%)

 

-Drug

651

7 (1.08%)

 

-Food, Rhinitis, pollen and others

1184

8 (0.68%)

 

Number of transfusion per patient

n = 20,230

n = 117

< 0.0001

-1

7816

21 (0.27%)

 

−2-5

9751

56 (0.57%)

 

−6-10

2195

61 (2.78%)

 

- > 11

468

13 (2.78%)

 

Products

n = 28,840

n = 236

< 0.0001

-PC

4292

142 (3.31%)

 

-SLRBC

11,571

26 (0.22%)

 

-FFP

12,801

64 (0.45%)

 

-Cryoprecipitate

176

4 (2.27%)

 

Department

n = 28,840

n = 236

< 0.0001

-Hematology-Oncology

6814

109 (1.59%)

 

-Surgical ICU

2162

19 (0.88%)

 

-Pediatric ICU

1876

5 (0.27%)

 

-Cardiothoracic surgery

3139

18 (0.57%)

 

-General surgery

2697

21 (0.78%)

 

-Outpatient

9321

47 (0.50%)

 

-Other

2831

17 (0.60%)

 

ATR type

 

n = 236

 

-urticaria

/

162 (68.64%)

 

-FNHTR

/

14 (5.93%)

 

-rash

/

16 (6.78%)

 

-erythema

/

16 (6.78%)

 

-skin itching

/

8 (3.39%)

 

-Others

/

20 (8.47%)

 
  1. ATR allergic transfusion reaction, PC platelet concentrate, SLRBC suspended leukocyte-reduced red blood cells, FFP fresh-frozen plasma, ICU intensive care unit, FNHTR non-hemolytic transfusion reactions