Case | Gestational Age | Birth Weight | Apgar score | TSV onset | Heart rate And hemodynamic parameters | NEC onset and clinical sings | Intrumental findings | Treatments | Others | References |
---|---|---|---|---|---|---|---|---|---|---|
1 | 29 + 6 Weeks | 1380 g | 1′: 7 5′: 8 | 16th day of life | - 300-390 bpm - Hemodynamically stable good perfusion | - 17th day of life - Bloody stools, abdominal distension | Abdominal X-rays: no evidence of pneumatosis | Parenteral nutrition; Antibiotics (ampicillin and gentamicin) | N.r. | clinical case of our observation and described in the text |
2 | 38 Weeks | 2755 g | N.r. | 13th day of life | - 278-294 bpm - Echocardiography: Normal heart anatomy; borderline and dyskinetic cardiac function; Left ventricle ejection fraction of 50% | - 16th day of life - Abdominal distension | Abdominal X-rays: dilated bowel loops with no free air in the abdomen. On contrast enema severe stenosis at the transverse colon, with dilated small bowel loops | Surgery: resection of the stenotic transverse colon with end-end anastomosis, and ileal resection of a stenotic segment (2 cm) with end-end anastomosis. | Laparotomy: Terminal ileum and a jejunal loop with omentum were solidly adherent to the stenotic transverse colon | Nakib et al. 2018 [14] |
3 | 36 Weeks | 2100 g (IUGR) | 1′: 5 5′: 6 10′: 7 | 3rd day of life | - 280 bpm - Hemodynamically stable. Echocardiogram: patent foramen ovale and a small patent ductus arteriosus | - 7th day of life - Rectal bleeding. Abdominal distension | Abdominal X-rays: no pneumatosis, portal venous gas or free air. Abdominal ultrasound: focal bowel wall echogenicities consistent with pneumatosis | Parenteral nutrition; Antibiotics (ampicillin, tobramycin and metronidazole) | Miller-Dieker syndrome. | Saini et al. 2017 [6] |
4 | 36 Weeks | N.r. (LGA) | 1′: 7 5′: 9 | 1st day of life | - 250 bpm - Echocardiogram: fenestrated atrial septum and restrictive patent ductus arteriosus | - 7th day of life - Bloody stools | Abdominal X-ray and abdominal ultrasound: colonic pneumatosis intestinalis | Parenteral nutrition; Antibiotics (vancomycin, tobramycin and metronidazole) | Wolff-Parkinson- White syndrome | Saini et al. 2017 [6] |
5 | 35 Weeks | 2200 g | 1′: 5 5′: 9 | Antenatal | - 240–250 bmp - Echocardiogram: structurally normal heart with good function | - 11th day of life - Emesis, abdominal distension | Abdominal X-ray: pneumatosis | Parenteral nutrition; Antibiotics Surgery: compromised bowel was resected | N.r. | Hanna et al. 2013 [15] |
6 | 41 Weeks | N.r | N.r. | 1 month of life | - N.r. - Echocardiogram: complex tricuspid atresia which a palliative BlalockTaussig shunt performed at 4 months of life | −5 months of life - N.r. | Abdominal X-ray: no gas consistent with ischemic injury or paralytic ileus. | Parenteral nutrition; Antibiotics Surgery: wide excision and anastomosis of ischemic small intestine | Facial and skeletal abnormalities. Laparotomy: an abscess involving the cecum and terminal part of small intestine | Hajivassiliou et al. 1998 [16] |
7 | N.r (Premature) | N.r. | N.r. | Antenatal | -N.r. - No signs of congestive heart failure | - 4th day of life - N.r. | N.r. | Fatal fulminant NEC | N.r. | Khalak et al. 1998 [17] |