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Table 1 The prevalence of Interon22 inversion mutation identified in severe and moderate hemophilia patients

From: Factor VIII inhibitor development in Egyptian hemophilia patients: does intron 22 inversion mutation play a role?

Degree

Severe HA N (%)

Moderate HA

N (%)

Total

N (%)

test

P value

Mutation

Inv22 positive

   

12.05

0.0005***

N (%)

24 (33)

3(6)

27 (23)

Inv22 negative

N (%)

48 (67)

45(94)

93 (77)

Total

72

48

120

  1. Inv22intron22 inversion, HA hemophilia A, N number, % percent, ***highly significant, test chi-square
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Italian Journal of Pediatrics

ISSN: 1824-7288

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