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Table 3 The Prevalence of FVIII Inhibitors among Interon22 inversion Positive and Negative Mutation Harboring Cases

From: Factor VIII inhibitor development in Egyptian hemophilia patients: does intron 22 inversion mutation play a role?

Inhibitors F VIII inhibitor positive
N (%)
F VIII inhibitor negative
N (%)
total
Mutation
Inv22 positive
N (%)
10 (37) 17 (63) 27
Inv22 negative
N (%)
11 (12) 82 (88) 93
Total 21 (18) 99 (82) 120
Chi-square 8.9
P value 0.002***
ODD Ratio (OR) 4.3
95% CI 1.6–11.9
P value 0.003***
  1. Inv22 intron22 inversion, F VIII factor VIII, N number, % percent, ***highly significant,