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Table 3 The Prevalence of FVIII Inhibitors among Interon22 inversion Positive and Negative Mutation Harboring Cases

From: Factor VIII inhibitor development in Egyptian hemophilia patients: does intron 22 inversion mutation play a role?

Inhibitors

F VIII inhibitor positive

N (%)

F VIII inhibitor negative

N (%)

total

Mutation

Inv22 positive

N (%)

10 (37)

17 (63)

27

Inv22 negative

N (%)

11 (12)

82 (88)

93

Total

21 (18)

99 (82)

120

Chi-square

8.9

P value

0.002***

ODD Ratio (OR)

4.3

95% CI

1.6–11.9

P value

0.003***

  1. Inv22 intron22 inversion, F VIII factor VIII, N number, % percent, ***highly significant,