Table 4 Prevalence of FVIII inhibitors Among Severely and Moderately Hemophilia Patients with Different Interon 22 inversion Mutation Status
| Inhibitor |
F VIII inhibitor positive N (%) |
F VIII inhibitor negative N (%) | Total |
|---|---|---|---|
|
Degree Mutation | |||
| Severe HA | 72 | ||
| Inv22 positive N (%) | 9 (38) | 15 (62) | 24 |
| Inv22 negative N (%) | 7 (15) | 41 (85) | 48 |
| Odd Ratio | 3.5 | ||
| 95% CI | 1.11–11 | ||
| P value | 0.032* | ||
| Moderate HA | 48 | ||
| Inv22 positive N (%) | 1 (33) | 2 (67) | 3 |
| Inv22 negative N (%) | 4 (9) | 41 (91) | 45 |
| Odd Ratio | 5.1 | ||
| 95% CI | 0.37–9.7 | ||
| P value | 0.2 # |