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Table 1 Patient details

From: Iatrogenic severe hyperglycemia due to parenteral administration of glucose in children – a case series

 

Pat. No.

Age and diagnosis

Glucose concentration and error type

Maximum serum glucose [mg/dl (mmol/l)]

Reduction of blood glucose

[mg/dl/h (mmol/l/h)]

Insulin therapy

Initial pH

Most altered Na + within first 24 h of hyperglycemia [mmol/l]

Sequelae

Good outcome

1

Newborn, preterm birth

G12.5%, individual PN, AE: infusion rate too high (prescribed 4.5 ml/h)

1000 (55.5)

240 (13.3)

No

7.30

140

None

2

Newborn, esophageal atresia

G40%, individual PN, AE: infusion rate too high (prescribed 1 ml/h)

2240 (124.3)

173 (9.6)

Yes

7.07

127

None

3

Infant, craniosynosthosis

G50%, AE: 33 ml/h instead of 3.3 ml/h

595 (33.0)

210 (11.7)

Yes

7.38

134

None

4

Child, after liver transplant

G20%, AE: bolus of glucose instead of cristalline solution

539 (29.9)

75 (4.2)

No

7.36

149

None

5

Child, after surgery

G50%, AE: infusion rate too high

800 (44.4)

None

6

Child, rhabdomyo-sarcoma

G70%, individual PN, error type unknown (prescribed infusion rate 24 ml/h)

983 (54.6)

91 (5.1)

Yes

n.d.

None

7

Child, acute lymphatic leukemia

ME: wrong composition of individual PN

840 (46.6)

113 (6.3)

Yes

6.96

163

None

Poor outcome

8

Newborn, preterm birth

G50%, individual PN, AE: infusion rate too high (prescribed 2.4 ml/h)

569 (31.6)

58 (3.2)

Yes

7.03

142

CP, psychomotor retardation

9

Infant, biliary atresia

Unknown glucose concentration, AE: individual PN, infusion rate too high (prescribed 15.8 ml/h)

1810 (100.5)

72 (4.0)

No

6.74

118

Died

10

Infant, gastroenteritis

G50%, PE: prescribed infusion rate too high

> 2000 (> 111.0)

Yes

n.d.

Died

11

Child, after bone marrow transplant

70% glucose, AE: 350 ml in 2 h instead of 30 ml/h

1900 (105.5)

205 (11.4)

Yes

7.02

159

Chronic renal failure

  1. G Glucose, PN Parenteral nutrition, CP Cerebral palsy, AE Administration error, PE Prescription error, ME Mixing error