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Table 2 Comparison of clinical parameters by outcome

From: Iatrogenic severe hyperglycemia due to parenteral administration of glucose in children – a case series

  All patients Poor outcome Good outcome
Number of patients n (%) n = 11 (100%) n = 4 (36%) n = 7 (64%)
Age group 3 newborns 1 newborn 2 newborns
3 infants 2 infants 1 infant
5 children 1 child 4 children
Ward non-ICU 4/11 (36%) 3/4 (75%) 1/7 (14%)
Occurrence during night or weekend 6/10 (60%) 2/4 (50%) 4/6 (67%)
Maximum glucose > 1500 mg/dl (83.3 mmol/l) 4/11 (36%) 3/4 (75%) 1/7 (14%)
Reduction of blood glucose > 100 mg/dl/hour (> 5.6 mmol/l/h) 5/9 (56%) 1/3 (33%) 4/6 (67%)
Hours to normoglycemia [median (range)] 7 (2–23) (n = 9) 8.5 (7–23) (n = 3) 6 (2–12) (n = 6)
Dysnatremia (Na+ < 130 or > 145 mmol/l) 5/8 (63%) 2/3 (67%) 3/5 (60%)
Dyskalemia (K+ < 3.5 or > 5.0 mmol/l) 6/9 (67%) 3/3 (100%) 3/6 (50%)
pH < 7.1 5/8 (63%) 3/3 (100%) 2/5 (40%)
Base excess < −10.0 mmol/l 3/8 (38%) 2/3 (67%) 1/5 (20%)
Lactate > 4 mmol/l 5/6 (83%) 2/2 (100%) 3/4 (75%)
Mechanical ventilation 8/11 (73%) 4/4 (100%) 4/7 (57%)
Vasopressor therapy 5/9 (56%) 2/3 (67%) 3/6 (50%)
Insulin therapy 7/10 (70%) 3/4 (75%) 4/6 (67%)
Dialysis 2/11 (18%) 2/4 (50%) 0/7 (0%)
Coma 5/8 (63%) 3/3 (100%) 2/5 (40%)
Seizures 5/11 (45%) 3/4 (75%) 2/7 (29%)