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Table 2 Comparison of clinical parameters by outcome

From: Iatrogenic severe hyperglycemia due to parenteral administration of glucose in children – a case series

 

All patients

Poor outcome

Good outcome

Number of patients n (%)

n = 11 (100%)

n = 4 (36%)

n = 7 (64%)

Age group

3 newborns

1 newborn

2 newborns

3 infants

2 infants

1 infant

5 children

1 child

4 children

Ward non-ICU

4/11 (36%)

3/4 (75%)

1/7 (14%)

Occurrence during night or weekend

6/10 (60%)

2/4 (50%)

4/6 (67%)

Maximum glucose > 1500 mg/dl (83.3 mmol/l)

4/11 (36%)

3/4 (75%)

1/7 (14%)

Reduction of blood glucose > 100 mg/dl/hour (> 5.6 mmol/l/h)

5/9 (56%)

1/3 (33%)

4/6 (67%)

Hours to normoglycemia [median (range)]

7 (2–23) (n = 9)

8.5 (7–23) (n = 3)

6 (2–12) (n = 6)

Dysnatremia (Na+ < 130 or > 145 mmol/l)

5/8 (63%)

2/3 (67%)

3/5 (60%)

Dyskalemia (K+ < 3.5 or > 5.0 mmol/l)

6/9 (67%)

3/3 (100%)

3/6 (50%)

pH < 7.1

5/8 (63%)

3/3 (100%)

2/5 (40%)

Base excess < −10.0 mmol/l

3/8 (38%)

2/3 (67%)

1/5 (20%)

Lactate > 4 mmol/l

5/6 (83%)

2/2 (100%)

3/4 (75%)

Mechanical ventilation

8/11 (73%)

4/4 (100%)

4/7 (57%)

Vasopressor therapy

5/9 (56%)

2/3 (67%)

3/6 (50%)

Insulin therapy

7/10 (70%)

3/4 (75%)

4/6 (67%)

Dialysis

2/11 (18%)

2/4 (50%)

0/7 (0%)

Coma

5/8 (63%)

3/3 (100%)

2/5 (40%)

Seizures

5/11 (45%)

3/4 (75%)

2/7 (29%)