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Table 1 (abstract A31). Demographic and clinical findings of enrolled population at day 1 and after 1 year

From: Abstracts from the 25th Italian Congress of Cystic Fibrosis and the 15th National Congress of Cystic Fibrosis Italian Society

Patients Baseline During NIV After 1 year P value
Age (years) 23.8±6.0    
LCI 17.4±3.1   15.5±2.7 <0.05
FEV1 % 41.3±12   39.9±2.1 ns
PaO2 (mmHg) 75.5±12   73.2±11 ns
PaCO2 (mmHg) 41.8.±2.2   39.0.±2.1 ns
Awake SpO2 (%) 96±0.8   96±0.4 ns
Awake respiratory rate 21.7±2.2   23.2±1.8 ns
Exacerbations/year 4.7±1.1   2.2±0.5 <0.001
PG Parameters     
Meannocturnal SpO2 (%) 91±1.0 94±1.0   <0.001
Time with SpO2<90% 9.1±3.2 3.4±1.7   <0.01
Mean TcCO2 (mmHg) 38.1±2.3 39.1±2.3   ns
AHI 0.6±0.4 0.5±0.4   ns
Mean nocturnal RR 28.4±4.2 23.5±1.9   <0.01
  1. LCI: Lung Clearence Index; FEV1: forced expiratory volume in 1 sec; RR: respiratory rate; PG: poligraphy; TcCO2 : Transcutaneous CO2 ; AHI: apnea-hypopnea index; RR: respiratory rate