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Table 1 (abstract A31). Demographic and clinical findings of enrolled population at day 1 and after 1 year

From: Abstracts from the 25th Italian Congress of Cystic Fibrosis and the 15th National Congress of Cystic Fibrosis Italian Society

Patients

Baseline

During NIV

After 1 year

P value

Age (years)

23.8±6.0

   

LCI

17.4±3.1

 

15.5±2.7

<0.05

FEV1 %

41.3±12

 

39.9±2.1

ns

PaO2 (mmHg)

75.5±12

 

73.2±11

ns

PaCO2 (mmHg)

41.8.±2.2

 

39.0.±2.1

ns

Awake SpO2 (%)

96±0.8

 

96±0.4

ns

Awake respiratory rate

21.7±2.2

 

23.2±1.8

ns

Exacerbations/year

4.7±1.1

 

2.2±0.5

<0.001

PG Parameters

    

Meannocturnal SpO2 (%)

91±1.0

94±1.0

 

<0.001

Time with SpO2<90%

9.1±3.2

3.4±1.7

 

<0.01

Mean TcCO2 (mmHg)

38.1±2.3

39.1±2.3

 

ns

AHI

0.6±0.4

0.5±0.4

 

ns

Mean nocturnal RR

28.4±4.2

23.5±1.9

 

<0.01

  1. LCI: Lung Clearence Index; FEV1: forced expiratory volume in 1 sec; RR: respiratory rate; PG: poligraphy; TcCO2 : Transcutaneous CO2 ; AHI: apnea-hypopnea index; RR: respiratory rate