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Table 3 Clinical characteristics of PBB in the western countries

From: Update on protracted bacterial bronchitis in children

Author

Pritchard MG [13]

Wurzel DF [14]

Narang R [15]

Chang AB [16]

Kompare M [17]

Donnelly D [18]

Marchant JM [1]

Year

2015

2014

2014

2012

2012

2007

2006

Research

R

P

R

P

R

R

P

Number

44

104

50

50

70

81

43

M(F)

72 (32)

36 (14)

50 (20)

40 (41)

Age

2.7y

(1.5–4.0)

19 m

(12-30 m)

2.9y

(1.7–4.4)

4.5y

3 m

3.9y

(5 m-14y)

2.6y

Course

11 m

(9–14.7 m)

28w

(6-57w)

11 m

(8-14 m)

>4w

1-60 m

5 m

>1 m

>3w

Antibiotic used

9

Bronchoscopy

44

104

50

50

70

19

43

Pathogen

 Hi

27 (61.3%)

75 (72.1%)

25 (50%)

5 (10%)

39 (55%)

65 (80%)

20 (46.5%)

 Mcat

22 (50%)

45 (43.3%)

14 (28%)

4 (8%)

41 (58.6%)

11 (25.5%)

 Spn

10 (22.7%)

41 (39.4%)

8 (16%)

19 (38%)

26 (37.1)

30 (37%)

15 (34.9%)

 Sa

8 (18.1%)

11 (22%)

4 (8%)

 Adv

22 (21.1%)

2 (4.6%)

 RSV

5 (4.8%)

 PIV

1 (2.3%)

Comorbidities

 Wheeze

63 (60.5%)

30 (60%)

39 (48.1%)

 Sinusitis

14 (28%)

 Airway stenosis

6 (12%)

 Tracheobronchial malacia

71 (68.2%)

5 (10%)

52

(74.2%)

Treatment

 Antibiotics

Amo /Cla

Amo

Amo /Cla

Amo /Cep /Azi

Amo

Amo

Amo

 Duration

6-8w

2w

6w

2-4w

2-4w

4-6w

2w

Follow-up

1-4y

1y

 

1y

Effects

  

    

 Remission

52

 Improve

33

104

50

61

43

 Relapse

25

43

Complication

  1. Values are expressed as n (%). R: retrospective research, P: prospective research. M: male; F: female. Hi: Haemophilus influenza; Mcat, Moraxella catarrhalis; Spn: Streptococcus pneumonia; Sa: Staphylococcus aureus; Adv:adenovirus; RSV:respiratory syncytial virus; PIV:parainfluenza virus. Amo:Amoxicillin-clavulanate; Cla: Clarithromycin; Cep: cephalosporin antibiotics; Azi: Azithromycin.