TY - JOUR AU - Dubaj, Cezary AU - Czyż, Katarzyna AU - Furmaga-Jabłońska, Wanda PY - 2020 DA - 2020/03/30 TI - Vitamin B12 deficiency as a cause of severe neurological symptoms in breast fed infant – a case report JO - Italian Journal of Pediatrics SP - 40 VL - 46 IS - 1 AB - Vitamin B12 (cobalamin, cbl) deficiency in children is rare and may occurs in exclusively breast fed infants of mothers on vegetarian or vegan diet with lack of appropriate supplementation. The clinical manifestation of vitamin B12 deficiency include neurological disorders, megaloblastic anemia and failure to thrive. Routine and commonly used laboratory tests such as cell blood count (CBC) or serum vitamin B12 level are sufficient for appropriate diagnosis. Typical therapy is based on intramuscular cobalamin injections. Early diagnosis and early onset of treatment are crucial factors for long-term prognosis of patients as the duration of deficiency may be correlated with the development of long lasting changes in the nervous system. SN - 1824-7288 UR - https://doi.org/10.1186/s13052-020-0804-x DO - 10.1186/s13052-020-0804-x ID - Dubaj2020 ER -