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Table 1 DIC diagnostic criteria of JSOGN

From: Risk factors and treatments for disseminated intravascular coagulation in neonates

BW≥ 1,500g< 1,500g
PLT70×103/μL ≤ and 50% reduction within 24 hours1 point1 point
50×103/μL ≤ < 70×103/μL1 point1 point
< 50×103/μL2 points2 points
Fibrinogen50mg/dL ≤ < 100mg/dL1 point-
< 50mg/dL2 points1 point
PT-INR1.6 ≤ < 1.81 point-
1.8 ≤2 points1 point
FDP or D-dimer< 2.5 fold upper limit of normal range-1 point-1 point
2.5 fold upper limit of normal range ≤ < 10 fold upper limit of normal range1 point1 point
10 fold upper limit of normal range ≤2 points2 points
  1. JSOGNH Japan Society of Obstetrical, Gynecological & Neonatal Hematology, PLT platelet count, BW birth weight, PT-INR prothrombin time international ratio
  2. For a platelet count of ≥ 70×103 /μL, a point is added if the platelet count is reduced by 50% within 24 hours. A point is not added if the patients had thrombocytopenia due to myelosuppression disease
  3. For fibrinogen, a point is added if the underlying disease of the patient was an infection
  4. Since the upper limit of D-dimer is different among D-dimer kits, a point is added if FDP and D-dimer increased by 2.5 or 10 fold of the upper limit of normal
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Italian Journal of Pediatrics

ISSN: 1824-7288

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