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Table 2 Characteristics of DIC and non-DIC neonates

From: Risk factors and treatments for disseminated intravascular coagulation in neonates

 DIC score ≥ 3 (n = 103)DIC score < 3 (n = 263)P-Value
GA (weeks) (median)29.436.4< 0.001
BW (g) (median)13421703< 0.001
IVH (%)21 (20)20 (8)< 0.01
SGA (%)28 (27)32 (12)< 0.01
Apgar Score (1 min) (median)35< 0.001
Apgar Score (5 min) (median)67< 0.001
Sepsis1 (1)0 (0)0.109
Birth Asphyxia (%)95 (92)213 (80)< 0.001
Low Apgar Score (%)27 (26)39 (14)< 0.01
RDS (%)29 (28)68 (26)0.65
Hemangioma2 (2)0 (0)< 0.05
Hydrops6 (6)4 (2)< 0.05
PIH16 (15)12 (5)< 0.01
PA15 (15)11 (4)< 0.01
PLT (× 103μl) (median)163237< 0.001
PT-INR (median)1.601.27< 0.001
aPTT (seconds) (median)78.460.9< 0.01
FBG (mg/dl) (median)91131< 0.001
D-dimer (ng/ml) (median)12.89.1< 0.001
AT activity (%) (median)27.536.0< 0.001
  1. GA Gestational age, IVH Intraventricular hemorrhage, BW birth weight, PT-INR Prothrombin time international ratio, RDS Respiratory distress syndrome, PIH Pregnancy induced hypertension, PA Placental abruption, DIC Disseminated intravascular coagulation, NS not significant
  2. GA Gestational age, BW Birth weight, IVH Intraventricular hemorrhage, SGA Small for gestational age, RDS respiratory distress syndrome, PIH pregnancy-induced hypertension, PA Placental abruption, PT-INR Prothrombin time international normalized ratio; GA, BW, Apgar score, PLT, PT-INR, aPTT, FBG, D-dimer, and AT were analyzed by Mann-Whitney U test. IVH, SGA, sepsis, birth asphyxia, low Apgar score, RDS, hemangioma, hydrops, Continuous variables were presented as median. PIH and PA (%) were analyzed by χ2 test