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Table 2 Characteristics of DIC and non-DIC neonates

From: Risk factors and treatments for disseminated intravascular coagulation in neonates

 

DIC score ≥ 3 (n = 103)

DIC score < 3 (n = 263)

P-Value

GA (weeks) (median)

29.4

36.4

< 0.001

BW (g) (median)

1342

1703

< 0.001

IVH (%)

21 (20)

20 (8)

< 0.01

SGA (%)

28 (27)

32 (12)

< 0.01

Apgar Score (1 min) (median)

3

5

< 0.001

Apgar Score (5 min) (median)

6

7

< 0.001

Sepsis

1 (1)

0 (0)

0.109

Birth Asphyxia (%)

95 (92)

213 (80)

< 0.001

Low Apgar Score (%)

27 (26)

39 (14)

< 0.01

RDS (%)

29 (28)

68 (26)

0.65

Hemangioma

2 (2)

0 (0)

< 0.05

Hydrops

6 (6)

4 (2)

< 0.05

PIH

16 (15)

12 (5)

< 0.01

PA

15 (15)

11 (4)

< 0.01

PLT (× 103μl) (median)

163

237

< 0.001

PT-INR (median)

1.60

1.27

< 0.001

aPTT (seconds) (median)

78.4

60.9

< 0.01

FBG (mg/dl) (median)

91

131

< 0.001

D-dimer (ng/ml) (median)

12.8

9.1

< 0.001

AT activity (%) (median)

27.5

36.0

< 0.001

  1. GA Gestational age, IVH Intraventricular hemorrhage, BW birth weight, PT-INR Prothrombin time international ratio, RDS Respiratory distress syndrome, PIH Pregnancy induced hypertension, PA Placental abruption, DIC Disseminated intravascular coagulation, NS not significant
  2. GA Gestational age, BW Birth weight, IVH Intraventricular hemorrhage, SGA Small for gestational age, RDS respiratory distress syndrome, PIH pregnancy-induced hypertension, PA Placental abruption, PT-INR Prothrombin time international normalized ratio; GA, BW, Apgar score, PLT, PT-INR, aPTT, FBG, D-dimer, and AT were analyzed by Mann-Whitney U test. IVH, SGA, sepsis, birth asphyxia, low Apgar score, RDS, hemangioma, hydrops, Continuous variables were presented as median. PIH and PA (%) were analyzed by χ2 test
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Italian Journal of Pediatrics

ISSN: 1824-7288

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