From: The epidemiology of hospital death following pediatric severe community acquired pneumonia
Days between Severe CAP Recognition and Death | ||||
---|---|---|---|---|
Variable | All | ≤ 7d | > 7d | P-value |
n | 57 | 20 | 37 | |
Age, months (median [IQR]) | 6 [4,9] | 3.5 [1.8,5] | 8 [6,13] | < 0.001 |
Female (%) | 28 (49.1) | 11 (55.0) | 17 (45.9) | 0.514 |
PRISM III (median [IQR]) 1 | 16 [13.3,21] | 23 [21,26] | 15 [12,16] | < 0.001 |
Comorbidity (%) | ||||
CHG | 20 (35.1) | 12 (60.0) | 8 (21.6) | 0.004 |
Respiratory dysplasia | 7 (12.3) | 3 (15.0) | 4 (10.8) | 0.970 |
Moderate/severe malnutrition 2 | 11 (19.3) | 6 (30.0) | 5 (13.5) | 0.249 |
Known chromosomal abnormality | 1 (1.8) | 1 (5.0) | 0 | |
Neurologic disorder | 1 (1.8) | 1 (5.0) | 0 | |
Immunocompromised | 1 (1.8) | 1 (5.0) | 0 | |
Prematurity | 6 (10.5) | 3 (15.0) | 3 (8.1) | 0.721 |
Cause of death (%) | 0.035 | |||
ARDS | 7 (12.3) | 3 (15.0) | 4 (10.8) | |
Cardiovascular dysfunction | 23 (40.4) | 12 (60.0) | 11 (29.7) | |
MODS | 27 (47.4) | 5 (25.0) | 22 (59.5) | |
Mode of death (%) | 0.167 | |||
Withdrawal/withholding therapies | 18 (31.6) | 4 (20.0) | 14 (37.8) | |
Unsuccessful CPR | 39 (68.4) | 16 (80.0) | 23 (62.2) | |
Hematologic | 9 (15.8) | 2 (10.0) | 7 (18.9) | 0.617 |
Pathogen (%) | ||||
Bacterial | 24 (42.1) | 9 (45.0) | 15 (40.5) | 0.745 |
Viral | 17 (29.8) | 5 (25.0) | 12 (32.4) | 0.558 |
Fungal | 3 (5.3) | 0 | 3 (8.1) | 0.492 |
Unknown | 26 (45.6) | 10 (50.0) | 16 (43.2) | 0.625 |
Days between Severe CAP Recognition and Death | ||||
Variable | All | ≤ 3d | > 3d | P-value |
Complicated infection | 13 (22.8) | 4 (20.0) | 9 (24.3) | 0.968 |