Skip to main content

Table 1 Demographics of the non-survivors

From: The epidemiology of hospital death following pediatric severe community acquired pneumonia

  

Days between Severe CAP Recognition and Death

 

Variable

All

≤ 7d

> 7d

P-value

n

57

20

37

 

Age, months (median [IQR])

6 [4,9]

3.5 [1.8,5]

8 [6,13]

< 0.001

Female (%)

28 (49.1)

11 (55.0)

17 (45.9)

0.514

PRISM III (median [IQR]) 1

16 [13.3,21]

23 [21,26]

15 [12,16]

< 0.001

Comorbidity (%)

 CHG

20 (35.1)

12 (60.0)

8 (21.6)

0.004

 Respiratory dysplasia

7 (12.3)

3 (15.0)

4 (10.8)

0.970

 Moderate/severe malnutrition 2

11 (19.3)

6 (30.0)

5 (13.5)

0.249

 Known chromosomal abnormality

1 (1.8)

1 (5.0)

0

 

 Neurologic disorder

1 (1.8)

1 (5.0)

0

 

 Immunocompromised

1 (1.8)

1 (5.0)

0

 

 Prematurity

6 (10.5)

3 (15.0)

3 (8.1)

0.721

Cause of death (%)

0.035

 ARDS

7 (12.3)

3 (15.0)

4 (10.8)

 

 Cardiovascular dysfunction

23 (40.4)

12 (60.0)

11 (29.7)

 

 MODS

27 (47.4)

5 (25.0)

22 (59.5)

 

Mode of death (%)

0.167

 Withdrawal/withholding therapies

18 (31.6)

4 (20.0)

14 (37.8)

 

 Unsuccessful CPR

39 (68.4)

16 (80.0)

23 (62.2)

 

 Hematologic

9 (15.8)

2 (10.0)

7 (18.9)

0.617

Pathogen (%)

 Bacterial

24 (42.1)

9 (45.0)

15 (40.5)

0.745

 Viral

17 (29.8)

5 (25.0)

12 (32.4)

0.558

 Fungal

3 (5.3)

0

3 (8.1)

0.492

 Unknown

26 (45.6)

10 (50.0)

16 (43.2)

0.625

Days between Severe CAP Recognition and Death

Variable

All

≤ 3d

> 3d

P-value

 Complicated infection

13 (22.8)

4 (20.0)

9 (24.3)

0.968

  1. IQR, interquartile range; PRISM, pediatric risk of mortality; CHG, congenital heart disease; ARDS, acute respiratory distress syndrome; MODS, multiple organ dysfunction syndrome; CPR, cardiopulmonary resuscitation
  2. 1 Data available for 54 patients due to lack of scoring for deaths prior to 12 h after ED/PICU admission
  3. 2 Moderate/severe malnutrition was defined as weight-for-age less than -2SD from means