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Table 1 Ibuprofen and chickenpox

From: Serious infectious events and ibuprofen administration in pediatrics: a narrative review in the era of COVID-19 pandemic

Year

1st author (Ref)

Children (N)

Disorder

Treatment

Adverse events

1997

Choo [26]

7865

Chickenpox

Ibuprofen

SSTI

1999

Zerr [23]

48

Chickenpox

Ibuprofen

Necrotizing fascitis

2001

Lesko [27]

224

Chickenpox

Ibuprofen +/−

GAS infections and

    

paracetamol

soft tissues necrosis

2008

Mikaeloff [28]

140,111

Chickenpox

Ibuprofen

Cellulitis, abscess,

    

(or other NSAIDs)

fasciitis and necrosis

2008

Souyry [29]

266

Chickenpox

Ibuprofen

Serious necrotising

   

and other

(or other NSAIDs)

soft-tissue infections

   

viral infections

  

2008

Dubos [30]

159

Chickenpox

Ibuprofen

Secondary bacterial

     

skin complications

  1. GAS Group A streptococci, N Number of enrolled children, NSAIDs Non-steroidal anti-inflammatory drugs, Ref Reference number, SSTI Skin and soft tissue infection