EOS risk categories | Management |
---|---|
High-risk patients | Full diagnostic evaluationab and empirical antibioticsc pending the results of the evaluation |
CRP and PCT at 24 ± 4 h of lifeb | |
CRP and PCT at 48 ± 4 h of lifeb | |
CRP and PCT at 72 ± 4 h of lifeb | |
Medium-risk patients | Limited diagnostic evaluationdb |
CRP and PCT at 24 ± 4 h of lifeb | |
CRP and PCT at 48 ± 4 h of lifeb | |
CRP and PCT at 72 ± 4 h of lifeeb | |
Further exams (CBC, blood culture)b and empirical antibioticsc in presence of one clinical indicator of EOS and one of the following conditions: 1) Abnormal cord blood PCTb; 2) Abnormal neonatal PCT before 28 h of lifeb; 3) Abnormal neonatal CRP and PCT after 28 h of lifeb | |
Low-risk patients | Routinely observation for ≥48 h before discharge |