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Table 3 Bivariable and multivariable logistic regression analysis of factors associated with virological failure among HIV positive children in Bahir Dar Town public health facility ART clinics, Northwestern Ethiopia, 2020 (n = 399)

From: Magnitude and associated factors of virological failure among children on ART in Bahir Dar Town public health facilities, Northwest Ethiopia: a facility based cross-sectional study

Factors

Virological failure,n (%)

COR(95% CI)

AOR(95% CI)

Yes

No

Age

 0–5 years

34 (21.7)

123 (78.3)

2.35 (1.10–5.01)

2.42 (1.02–5.74)**

 6–9 years

15 (10.2)

132 (89.8)

0.97 (0.42–2.25)

1.04 (0.42–2.58)

 10–15 years

10 (10.5)

85 (89.5)

1

1

Sex

 Male

35 (17.1)

170 (82.9)

1.46 (0.83–2.56)

1.27 (0.68–2.36)

 Female

24 (12.4)

170 (87.6)

1

1

Place of residence

 Outside of Bahir Dar

14 (19.4)

58 (80.6)

1.51 (0.78–2.94)

1.80 (0.84–3.86)

 Bahir Dar

45 (13.8)

282 (86.2)

1

1

Type of health facility

 Health-center

27 (18)

123 (82)

1.49 (0.85–2.60)

1.69 (0.89–3.22)

 Hospital

32 (12.9)

217 (87.1)

1

1

Child’s HIV status disclosure

 Not disclosed

23 (19.5)

95 (80.5)

1.65 (0.93–2.93)

0.85 (0.42–1.72)

 Disclosed

36 (12.8)

245 (87.2)

1

1

Baseline WHO clinical Staging

 Stage III/IV

21 (30)

49 (70)

3.28 (1.78–6.06)

2.32 (1.14–4.74)**

 Stage I/II

38 (11.6)

291 (88.4)

1

1

Opportunistic infection

 Yes

33 (26)

94 (74)

3.32 (1.89–5.85)

2.19 (1.13–4.25)**

 No

26 (9.6)

246 (90.4)

1

1

WHO clinical Staging (last visit)

 Stage III/IV

7 (33.3)

14 (66.7)

3.14 (1.21–8.13)

1.36 (0.44–4.16)

 Stage I/II

52 (13.8)

326 (86.2)

1

1

Regimen change/substitute

 Yes

51 (15.8)

271 (84.2)

1.62 (0.74–3.58)

1.53 (0.63–3.72)

 No

8 (10.4)

69 (89.6)

1

1

Interruption and restart

 Yes

18 (27.3)

48 (72.7)

2.67 (1.42–5.03)

2.21 (1.09–4.54)**

 No

41 (12.3)

292 (87.7)

1

1

ART adherence

 Fair/Poor

20 (29.4)

48 (70.6)

3.12 (1.68–5.80)

2.19 (1.05–4.57)**

 Good

39 (11.8)

292 (88.2)

1

1

Duration on ART

  ≥ 25 months

53 (15.7)

285 (84.3)

1.71 (0.70–4.16)

2.17 (0.81–5.86)

  < 25 months

6 (9.8)

55 (90.2)

1

1