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Table 1 Electronic survey sent to the Italian neonatologists

From: Management of oxygen saturation monitoring in preterm newborns in the NICU: the Italian picture

Infrastructure variables

 1. Your NICU is based in a:

2. Your NICU is:

  ▪ II level hospital

▪ South of Italy

  ▪ III level hospital

▪ North of Italy Center of Italy

 3. Is yours a University hospital?

4. Indicate the annual number of births in your hospital

  ▪ Yes

 

  ▪ No

 

 5. Indicate the annual number of newborns with gestational age < 32 weeks assisted in your NIC

 6. Indicate the annual number of newborns with gestational age < 28 weeks assisted in your NICU

 7. How many NICU beds does your NICU have

8. Which are the doctors/beds ratio in your NICU?

 9. Which is the nurses/beds ratio in your NICU?

10. Is there a local oxygen management protocol in your NICU?

▪ Yes

▪ No

 11. Indicate the minimum and maximum values of the range of SatO2 used in its NICU for newborns with gestational age less than 32 weeks requiring oxygen supply

 12. In which conditions may the above ranges vary?

  ▪ Never

  ▪ Variation in ventilator support mode (e.g. from not invasive to invasive)

  ▪ Presence of associated comorbidity (anemia, congenital cardiopathy, retinopathy of prematurity, need for surgery, sepsis)

  ▪ Other (explain here your answer)

 13. In case of SpO2 range variation, which of the two alarms is modified?

  ▪ Lower value alarm

  ▪ Upper value alarm

  ▪ Both

 14. Who is in charge of setting the minimum and maximum alarms?

  ▪ Chief

  ▪ Neonatologist

  ▪ Nurse

 15. Who is in charge to change the alarm value?

(You can choose more than one answer)

16. Who is in charge to disable the maximum alarm?

(You can choose more than one answer)

  ▪ Chief

▪ Chief

  ▪ Neonatologist

▪ Neonatologist

  ▪ Nurse

Nurse

 17. In which conditions are the alarms disabled?

(You can choose more than one answer)

  ▪ Never

  ▪ During invasive procedures (such as CVC insertion, chest drainage, reintubation)

  ▪ During nursing care (washing, weight evaluation, change of the diaper)

  ▪ patient respiratory instability

  ▪ Other (explain here your answer)

 18. If the alarms are disabled, which of the two alarms is disabled?

 19. Lower alarm

 20. Upper alarm

 21. Both

 22. Who responds to the alarm signal?

23. Is there written documentation of the interventions in

▪ Doctor on duty

24. response to the alarm signal?

  ▪ Nurse

▪ Yes

  ▪ Indifferently the doctor or the nurse

▪ No

Training related variables

 1. Is there a staff training program on the use of the pulse oximeter and on the rationale for careful monitoring of O2 saturation?

  ▪ Yes

  ▪ No

 2. Is there a formal staff training on how to respond to alarms?

  ▪ Yes

  ▪ No

Technology variables

 1. Indicate the type of the pulse oximeter in use in your NICU

 2. Is an O2 saturation daily plot available ​​for admitted newborns?

  ▪ Yes

  ▪ No

 3. If you answered yes to the previous question, is it possible to archive daily data?

  ▪ Yes

  ▪ No

Staff variables

 1. Do you think that a high alarm frequency during the work shift leads to latency in response time to the alarm or a decreased attention to that?

  ▪ Yes

  ▪ No

 2. If you answered yes, for what kind of alarm do you think that happens?

 3. Lower alarm

 4. Upper alarm

 5. Both

 6. In case of severe conditions, with frequent activation of the alarm, is there a progressive latency in the response time to the upper value alarm?

  ▪ Yes

  ▪ No

 7. Is the acoustic intensity of the alarms reduced during the night shift?

8. During the night shift, can the upper value alarm be changed / disabled?

  ▪ Yes

▪ Yes, it can be changed

  ▪ No

▪ Yes, it can be disabled

 

▪ No

 9. 1Are alarms disabled during assistance maneuvers (e.g. washing, suction, weight evaluation, nursing care)?

  ▪ Yes

  ▪ No

 10. If you answered yes, how long are they disabled on average?

11. During the execution of the assistance maneuvers, does the healthcare professional use supplemental oxygen?

  ▪ Less than 5 min

▪ Yes

  ▪ From 5 to 10 min

▪ No

  ▪ More than 10 min

 12. Before carrying out invasive maneuvers (e.g. reintubation, positioning of the thoracic drainage, CVC insertion, etc.) is a further supplementation of oxygen used, compared to that already administered?

  ▪ Yes

  ▪ No

Patient-related variables

 1. How many newborns less than 32 weeks of gestational age with respiratory support are currently hospitalized in your NICU?

 2. How many of the newborns mentioned in the previous question are assisted with non-invasive ventilation?

3. How many of the newborns mentioned in the previous question are assisted with invasive ventilation?

 4. Indicate the minimum and maximum values ​​of the SatO2 range used for currently hospitalized newborns with GA < 32 weeks

 5. Do the clinical conditions of the newborn (anemia, hypotension, apnea, infections, need for mechanical ventilation) influence the saturation range set?

6. In your NICU, do you have NIRS as an additional tissue oxygenation monitoring system?

  ▪ Yes

▪ Yes

  ▪ No

▪ No

 7. In your NICU, do you have the VEGF dosage as an additional tissue oxygenation monitoring tool?

8. Is there the possibility to measure oxidative stress by dosing specific biomarkers?

  ▪ Yes

▪ Yes

  ▪ No

▪ No

  1. NICU neonatal intensive care unit; SpO2 oxygen saturation; CVC catheter venous central; VEGF Vascular-Endothelial Growth Factor; NIRS near infrared spectroscopy