Skip to main content

Table 1 Review of clinical, imaging, and genetic aspects of EE patients

From: Symptomatic eating epilepsy: two novel pediatric patients and review of literature

authors, year [Ref]

n° of EE cases

mean age at eating sz onset (y)

sex (M/F)

trigger stimuli

imaging findings

genetic analysis

Singh et al., 2019 [29]

12

13.5 y

11 M; 1 F

eating alone (75%); eating + anxiety; eating + bathing; eating + spontaneously

normal (7 pts);

+  5 pts. (41.6%), focal/bilateral sclerosis or gliosis

na

von Stülpnagel et al., 2019 [2]

8

6.9 y

4 M; 4 F

biting; eating; chewing; oral sensory stimuli

normal

SYNGAP1 mutations

Jagtap et al.,

2016 [4]

47

14.3 ± 9.8 y

41 M; 6 F

eating; eating rice made food; oral sensory stimuli

+  16 pts. (34%), mainly PC lesions

na

Yacubian et al.,

2014 [30]

3

15 y

3 F

eating (independently of type of food)

normal

probably genetic due to familial clustering, but tested negative

Sillanpää et al.,

2014 [9]

1

0 y

F

breast feeding

normal

na

Patel et al.,

2013 [31]

6

11.3 ± 2.16 y

3 M; 3 F

eating; eating rice made food; “thinking of eating”

+  5 pts. (83.3%), perysilvian F lobe and high F lesions

na

Kokes et al.,

2013 [32]

6

20.3 y

4 M; 2 F

chewing; swallowing; oral sensory stimuli

+  4 pts. (66.7%), L hemisphere lesions

na

de Palma et al.,

2012 [10]

1

6 y

M

eating; oral and gustatory sensory

stimuli (mainly spicy food)

normal

MECP2 duplication

Roche Martínez et al., 2011 [11]

1

16 y

F

eating (independently of type of food)

normal

Rett syndrome but MECP2, CDKL5, FOXG1 tested negative

Bae et al.,

2011 [12]

2

39.5 y

1 M; 1 F

eating (independently of type of food)

normal

na

d’Orsi et al.,

2007 [33]

1

25 y

M

chewing; eating;

swallowing

+ bilateral opercular

dysplasia

na

Loreto et al.,

2000 [13]

3

22.7 y

2 M; 1 F

eating; sensory stimuli

+  2 pts. (66.7%), not specific

na

Mandal et al.,

1992 [34]a

20

na

16 M; 4 F

eating; eating Indian, rice made food/ heavy meals

normal (in 7 pts. tested)

na

Koul et al.,

1991 [35]a

78

na

na

eating; swallowing

na

na

Senanayake,

1990 [5]

20

20 y

na

eating

na

probably genetic due to familial clustering

Koul et al.,

1989 [14]

50

23.8 y

na

chewing; eating rice made food; swallowing

na

na

Loiseau et al.,

1986 [36]

2

20.5 y

2 M

chewing (mainly);

eating

na

na

Nagaraja et al.,

1984 [15]

13

14 y

8 M; 5 F

chewing; eating Indian, rice made food/heavy meals; drinking

na

na

Aguglia et al.,

1983 [3]

3

21.3 y

2 M; 1 F

chewing; eating

(independently of type of food)

na

na

Ahuja et al.,

1980 [16]

3

21.7 y

3 M

eating (only at home in 2 cases; both at home and outside in 1 case)

na

na

Robertson et al.,

1979 [37]

1

14 y

M

eating (independently of type of food)

+ internal capsule astrocytoma (involvement of the right caudate nucleus)

na

Cirignotta et al.,

1977 [38]

1

16 y

F

eating (independently of type of food)

na

na

Scollo-Lavizzari et al.,

1967 [39]

1

12 y

M

chewing; eating;

swallowing; sensory stimuli

na

na

  1. EE eating epilepsy, F female, F frontal, L left, M male, n number, na not available, PC posterior cortex, pts. patients, sz seizures, y years
  2. aonly Abstract available