Table 4 Association between HLA class risk and clinical and serological variables (univariate analysis)

Male

117 (39%)

25 (45.5%)

21 (29.6%)

41 (41%)

8 (34.8%)

22 (43.1%)

0.364

Age at onset

6.7 ± 4.2

6.7 ± 4.5

6.2 ± 4.1

6.7 ± 4

8.5 ± 5.3

6.3 ± 3.8

0.235

Family history

57 (19%)

14 (25%)

12 (17%)

21 (21%)

1 (4.3%)

9 (18%)

0.265

Anti-tTG ≥ 100

194 (64.7%)

44 (80%)

48 (67.6%)

56 (56%)

16 (69.6%)

30 (58.8%)

0.037

AI disorders^a

33 (11%)

6 (10.9%)

5 (7%)

12 (12%)

1 (4.3%)

9 (17.6%)

0.664

Atopy

97 (32.3%)

19 (34.5%)

19 (26.8%)

32 (32%)

8 (34.8%)

19 (37.3%)

0.779

Hypertransaminasemia

74 (24.7%)

9 (16.4%)

28 (39.4%)

25 (25%)

6 (26.1%)

6 (11.8%)

0.005

Marsh 3b/3c^b

89 (61.8%)

18 (75%)

17 (74%)

28 (50%)

4 (50%)

22 (67%)

0.125