From: Sleep problems among children with Fetal Alcohol Spectrum Disorders (FASD)- an explorative study
FASD patients (n = 19) | Control group (n = 5) | PSG laboratory control group (n = 105) | p | |
---|---|---|---|---|
Age, years | 7.1 (5.5; 9.3) | 7.5 (6.7; 8.7) | 6.5 (4.9; 8.9) | 0.7 |
Male sex, n (%) | 8 (42) | 3 (60) | 66 (63) | 0.2 |
Aquisition time, min | 594 (578; 607) | 582 (570; 584) | 591 (572; 603) | 0.4 |
TIB, min | 548 (530; 569) | 538 (529; 544) | 543 (524; 563) | 0.8 |
TST, min | 464 (434; 507) | 449 (446; 480) | 466 (433; 494) | 0.9 |
SPT, min | 526 (502; 543) | 512 (509; 534) | 517 (494; 537) | 0.8 |
Sleep efficiency, %TIB | 86.4 (78.4; 91.1) | 82.6 (81.4; 82.9) | 86.1 (79.7; 92.8) | 0.8 |
Sleep latency, min | 22.5 (7.4; 28,6) | 18.9 (11.0; 30.2) | 16.0 (5.5; 26.1) | 0.5 |
Stage shifts, n | 86 (64; 97) | 75 (57; 98) | 67 (54; 83) | 0.03 a |
W, %SPT | 9.7 (3.4; 14.7) | 12.3 (11.9; 16.5) | 9.8 (4.2; 15.2) | 0.6 |
N1, %TST | 4.3 (2.6; 5.7) | 3.2 (3.0; 3.7) | 2.4 (1.8; 3.6) | 0.005 a |
N2, %TST | 53.7 (47.6; 58.0) | 54.4 (47.4; 57.3) | 50.4 (46.2; 53.5) | 0.1 |
N3, %TST | 27.5 (22.1; 31.5) | 26.8 (24.6; 29.8) | 29.0 (25.0; 32.5) | 0.2 |
REM, %TST | 15.1 (14.5; 19.4) | 17.8 (17.4; 19.9) | 17.6 (14.9; 20.6) | 0.4 |
N3 + REM, %TST | 42.5 (39.5; 46.5) | 42.5 (37.0; 50.5) | 46.7 (42.1; 50.5) | 0.03 a |
Arousal index, events/h | 6.9 (5.9; 8.5) | 8.5 (7.7; 9.6) | 5.1 (4.1; 6.2) | < 0.0001 a,b |
Total apnea index, events/h | 1.0 (0.7; 1.8) | 2.1 (0.8; 5.4) | 0.3 | |
Central apnea index, events/h | 1.0 (0.5; 1.8) | 2.0 (0.8; 4.3) | 0.3 | |
Obstructive apnea index, events/h | 0 (0; 0.2) | 0 (0; 0.6) | 0.6 | |
Mixed apnea index, events/h | 0 (0; 0.1) | 0.1 (0; 0.1) | 0.6 | |
Hypopnea index, events/h | 0.5 (0; 1.2) | 0.8 (0.2; 1.6) | 0.5 | |
Obstructive apnea hipopnea Index, events/h | 0.7 (0.2; 1.3) | 0.98 (0.25; 2.75) | 0.6 | |
Respiratory disturbance index, events/h | 1.7 (1.0; 3.2) | 2.9 (0.8; 7.0) | 0.6 | |
Minimal SaO2, % | 91 (90; 92) | 92 (86; 92) | 0.5 | |
Average SaO2, % | 97 (96; 97) | 97 (96; 97) | 1 | |
Oxygen desaturation index, events/h | 1.8 (0.9; 2.9) | 2.2 (0.8; 8.1) | 0.5 |