Table 1 Demographic and Clinical Characteristics of the Study Population
Bio-Demographic Data | At Diagnosis (N = 477) | At Enrollment (N = 477) | McNemar Test (95% C.I) | P value |
|---|---|---|---|---|
Study center | ||||
 - Menofia No (%) | 196 (41) | |||
 - Zagazig No (%) | 281 (59) | |||
Gender | ||||
 - Male | 262 (55) | |||
 - Female | 215 (45) | |||
Age (years) | ||||
 - Mean (SD) | 1.5 (±1.5) | 9.9 (±5.1) | – | – |
 - Range | 0.5–9 | 2–18 |  |  |
Body Built No (%) | ||||
 - Underweight | 137 (29) | 280 (59) | 29.98 (25: 34) | < 0.0001 |
 - Normal | 291 (61) | 182 (38) | −22 (−26: −19) | < 0.0001 |
 - Overweight | 49 (10) | 15 (3) | −7 (−9: −4.8) | < 0.0001 |
Clinical Presentation No (%) | ||||
 - Pallor | 477 (100) | 477 (100) |  |  |
 - Jaundice | 438 (91) | 343 (72) | −9.85 (−12.5: −7) | < 0.0001 |
 - Hepatomegaly | 267 (56) | 368 (77) | 21 (17.5: 24.8) | < 0.0001 |
 - Splenomegaly | 372 (78) | 259 (54) a | – |  |
 - Skeletal Changes | 0 (0) | 393 (82) | 82 (79: 86.5) | < 0.0001 |