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Table 1 Demographic and Clinical Characteristics of the Study Population

From: CMV, B and C hepatitis among multi-transfused hereditary hemolytic Anemia children: an updated Egyptian experience

Bio-Demographic Data At Diagnosis
(N = 477)
At Enrollment
(N = 477)
McNemar Test
(95% C.I)
P value
Study center
 - Menofia No (%) 196 (41)
 - Zagazig No (%) 281 (59)
Gender
 - Male 262 (55)
 - Female 215 (45)
Age (years)
 - Mean (SD) 1.5 (±1.5) 9.9 (±5.1)
 - Range 0.5–9 2–18   
Body Built No (%)
 - Underweight 137 (29) 280 (59) 29.98 (25: 34) < 0.0001
 - Normal 291 (61) 182 (38) −22 (−26: −19) < 0.0001
 - Overweight 49 (10) 15 (3) −7 (−9: −4.8) < 0.0001
Clinical Presentation No (%)
 - Pallor 477 (100) 477 (100)   
 - Jaundice 438 (91) 343 (72) −9.85 (−12.5: −7) < 0.0001
 - Hepatomegaly 267 (56) 368 (77) 21 (17.5: 24.8) < 0.0001
 - Splenomegaly 372 (78) 259 (54) a  
 - Skeletal Changes 0 (0) 393 (82) 82 (79: 86.5) < 0.0001
  1. a165 patients (33%) are splenectomized
  2. SD standard deviation, CI Confidence Interval