Table 1 HLA typing, at high resolution of the DNA of the two patients and of all the family members, by next generation sequencing (NGS) by haplotype segregation
From: Vernal keratoconjunctivitis in twins: case report and literature review
Family Relationship | Haplotype | HLA-A* | HLA-B* | HLA-C* | HLA-DRB1* | HLA-DQB1* | HLA-DRB3* | HLA-DQA1* | HLA-DPB1* |
|---|---|---|---|---|---|---|---|---|---|
Father | a | 03:01:01 | 35:01:01 | 04:01:01 | 01:01:01 | 05:01 | – | 01:01:01 | 04:02P |
Father | b | 03:01:01 | 35:01:01 | 07:04:01 | 11:01:01 | 03:01P | 02:02:01 | 05:05:01 | 04:01P |
Mother | c | 32:01:01 | 15:17:01 | 07:01:02 | 13:02:01 | 06:04:01 | 03:01:01 | 01:02:01 | 04:01P |
Mother | d | 01:01:01 | 18:01:01 | 12:03:01 | 11:04:01 | 03:01P | 02:02:01 | 05:05:01 | 14:01P |
Patient 1 | a | 03:01:01 | 35:01:01 | 04:01:01 | 01:01:01 | 05:01 | – | 01:01:01 | 04:02P |
Patient 1 | c | 32:01:01 | 15:17:01 | 07:01:02 | 13:02:01 | 06:04:01 | 03:01:01 | 01:02:01 | 04:01P |
Patient 2 | a | 03:01:01 | 35:01:01 | 04:01:01 | 01:01:01 | 05:01 | – | 01:01:01 | 04:02P |
Patient 2 | c | 32:01:01 | 15:17:01 | 07:01:02 | 13:02:01 | 06:04:01 | 03:01:01 | 01:02:01 | 04:01P |