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Table 2 Characteristics of NB with chromosome 10 abnormality

From: Chromosome 10 abnormality predicts prognosis of neuroblastoma patients with bone marrow metastasis

Characteristic

N

%

chromosome 10

 Gain

3

23.1

 Loss

6

46.2

 Structural anomaly

4

30.8

Sex

 Male

6

46.2

 Female

7

53.8

MYCN

 Amplification

10

76.9

 Not amplification

3

23.1

1p36

 Lost

8

61.5

 Not lost

3

23.1

 None

2

15.4

LDH (U/L)

 ≤295

0

0

 295–500

3

23.1

 500–1500

0

0

 >1500

10

76.9

NSE (ng/l)

 ≤25

1

7.7

 25–100

0

0

 >100

12

92.3

VMA (mg/24 h urine)

 ≤13.6

5

38.5

 >13.6

7

53.8

 None

1

7.7

Primary tumor size

 ≤5

0

0

 5–10

4

30.8

 >10

8

61.5

Metastasis site

 Bone

10

76.9

 Bone marrow

13

100

 Harnpan/Intracalvarium

9

69.2

 Periorbital

5

38.5

 Mediastinum

4

30.8

 Lymph nodes

11

84.6

 Other visceral organ

5

38.5

  1. MYCN amplification of the MYCN gene, 1p36 loss of 1p36, LDH lactate dehydrogenase, NSE Neuron specific enolase, VMA Vanillylmandelic acid