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Table 2 Characteristics of NB with chromosome 10 abnormality

From: Chromosome 10 abnormality predicts prognosis of neuroblastoma patients with bone marrow metastasis

Characteristic N %
chromosome 10
 Gain 3 23.1
 Loss 6 46.2
 Structural anomaly 4 30.8
Sex
 Male 6 46.2
 Female 7 53.8
MYCN
 Amplification 10 76.9
 Not amplification 3 23.1
1p36
 Lost 8 61.5
 Not lost 3 23.1
 None 2 15.4
LDH (U/L)
 ≤295 0 0
 295–500 3 23.1
 500–1500 0 0
 >1500 10 76.9
NSE (ng/l)
 ≤25 1 7.7
 25–100 0 0
 >100 12 92.3
VMA (mg/24 h urine)
 ≤13.6 5 38.5
 >13.6 7 53.8
 None 1 7.7
Primary tumor size
 ≤5 0 0
 5–10 4 30.8
 >10 8 61.5
Metastasis site
 Bone 10 76.9
 Bone marrow 13 100
 Harnpan/Intracalvarium 9 69.2
 Periorbital 5 38.5
 Mediastinum 4 30.8
 Lymph nodes 11 84.6
 Other visceral organ 5 38.5
  1. MYCN amplification of the MYCN gene, 1p36 loss of 1p36, LDH lactate dehydrogenase, NSE Neuron specific enolase, VMA Vanillylmandelic acid