Skip to main content

Table 1 Demographic, clinical and treatment characteristics of mothers and neonates

From: Maternal and neonatal risk factors for neonatal respiratory distress syndrome in term neonates in Cyprus: a prospective case–control study

  NRDS
(n = 55)
No NRDS
(n = 79)
pvalue
Categorical
 Female (%) 14/55 (25.5) 37/78 (47.4) 0.01
 Smoking during pregnancy (%) 1/48 (2.01) 5/75 (6.7) 0.250
 Gestational diabetes (%) 7/47 (14.9) 11/74 (14.9) 0.997
 Thrombophilia (%) 1/48 (2.1) 3/75 (4.0) 0.559
 Caesarean section (%) 32/55 (58.2) 39/79 (49.4) 0.315
 Elective Caesarean (%) 29/32 (90.1) 21/39 (53.9) 0.001
 IUGR (%) 1/51 (2.0) 7/74 (9.5) 0.092
 Chorio-amnionitis (%) 0/45 (0.0) 1/74 (1.4) 0.434
 Oligo-hydramnios (%) 2/45 (4.4) 1/77 (1.3) 0.279
 Preeclampsia (%) 1/50 (2.0) 3/76 (4.0) 0.542
 Prenatal steroids (%) 5/49 (10.2) 9/76 (11.8) 0.777
 Fetal distress (%) 16/49 (32.7) 13/67 (19.4) 0.104
 Frequent OB visits (%) 46/53(86.8) 75/79(95.0) 0.097
 Blood transfusion (any) (%) 40/55 (72.7) 15/79 (18.9%) < 0.001
 Resuscitation at birth (%) 24/52 (46.2) 14/63 (22.2) 0.007
 Plasma transfusion (%) 38/55 (69.1) 12/79 (15.2%) < 0.001
 RBC transfusion (%) 14/55 (25.4) 4/79 (5.1%) 0.001
 Platelets transfusion (%) 2/55 (3.6) 1/79 (1.3%) 0.362
 Dopamine administration (%) 33/55 (60.0) 3/79 (3.8%) < 0.001
 Dobutamine administration (%) 17/55 (30.9) 1/79 (1.3%) < 0.001
Continuous
 Gestational Age (weeks) 38.3 (37.96, 38.62) 38.6 (38.3–38.8) 0.100*
 Birthweight (gr) 3146 (3035, 3256) 3160 (3044–3276) 0.866
 Maternal Age (years) 31.1 (29.9, 32.3) 30.8 (29.6–31.9) 0.696
 Maternal BMI (kg/m2) 23.8 (22.1, 25.4) 23.7 (22.4–25.1) 0.970*
 pH 7.31 (7.28,7.34) 7.40 (7.37–7.42) < 0.001
 Base Excess −6.72 (−7.78, −5.66) −4.92 (− 5.58, − 4.26) 0.004
 Parenteral nutrition (days) 8.24 (3.96, 12.52) 1.51 (1.02, 1.99) < 0.001
 Intravenous Antibiotics (days) 6.98 (6.38, 7.58) 5.86 (4.58, 7.15) 0.115
 Apgar at 5 min 8.92 (8.6–9.3) 9.46 (9.2–9.7) 0.002*
  1. IUGR Intrauterine Growth Restriction, OB Obstetrician, RBC Red blood cells, BMI Body mass Index
  2. *Mann Whitney U Test for comparison of medians