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Table 1 Demographic, clinical and treatment characteristics of mothers and neonates

From: Maternal and neonatal risk factors for neonatal respiratory distress syndrome in term neonates in Cyprus: a prospective case–control study

 

NRDS

(n = 55)

No NRDS

(n = 79)

pvalue

Categorical

 Female (%)

14/55 (25.5)

37/78 (47.4)

0.01

 Smoking during pregnancy (%)

1/48 (2.01)

5/75 (6.7)

0.250

 Gestational diabetes (%)

7/47 (14.9)

11/74 (14.9)

0.997

 Thrombophilia (%)

1/48 (2.1)

3/75 (4.0)

0.559

 Caesarean section (%)

32/55 (58.2)

39/79 (49.4)

0.315

 Elective Caesarean (%)

29/32 (90.1)

21/39 (53.9)

0.001

 IUGR (%)

1/51 (2.0)

7/74 (9.5)

0.092

 Chorio-amnionitis (%)

0/45 (0.0)

1/74 (1.4)

0.434

 Oligo-hydramnios (%)

2/45 (4.4)

1/77 (1.3)

0.279

 Preeclampsia (%)

1/50 (2.0)

3/76 (4.0)

0.542

 Prenatal steroids (%)

5/49 (10.2)

9/76 (11.8)

0.777

 Fetal distress (%)

16/49 (32.7)

13/67 (19.4)

0.104

 Frequent OB visits (%)

46/53(86.8)

75/79(95.0)

0.097

 Blood transfusion (any) (%)

40/55 (72.7)

15/79 (18.9%)

< 0.001

 Resuscitation at birth (%)

24/52 (46.2)

14/63 (22.2)

0.007

 Plasma transfusion (%)

38/55 (69.1)

12/79 (15.2%)

< 0.001

 RBC transfusion (%)

14/55 (25.4)

4/79 (5.1%)

0.001

 Platelets transfusion (%)

2/55 (3.6)

1/79 (1.3%)

0.362

 Dopamine administration (%)

33/55 (60.0)

3/79 (3.8%)

< 0.001

 Dobutamine administration (%)

17/55 (30.9)

1/79 (1.3%)

< 0.001

Continuous

 Gestational Age (weeks)

38.3 (37.96, 38.62)

38.6 (38.3–38.8)

0.100*

 Birthweight (gr)

3146 (3035, 3256)

3160 (3044–3276)

0.866

 Maternal Age (years)

31.1 (29.9, 32.3)

30.8 (29.6–31.9)

0.696

 Maternal BMI (kg/m2)

23.8 (22.1, 25.4)

23.7 (22.4–25.1)

0.970*

 pH

7.31 (7.28,7.34)

7.40 (7.37–7.42)

< 0.001

 Base Excess

−6.72 (−7.78, −5.66)

−4.92 (− 5.58, − 4.26)

0.004

 Parenteral nutrition (days)

8.24 (3.96, 12.52)

1.51 (1.02, 1.99)

< 0.001

 Intravenous Antibiotics (days)

6.98 (6.38, 7.58)

5.86 (4.58, 7.15)

0.115

 Apgar at 5 min

8.92 (8.6–9.3)

9.46 (9.2–9.7)

0.002*

  1. IUGR Intrauterine Growth Restriction, OB Obstetrician, RBC Red blood cells, BMI Body mass Index
  2. *Mann Whitney U Test for comparison of medians