Table 1 Classification of Infant’s Clinical Presentation according to NSC (available at https://neonatalsepsiscalculator.kaiserpermanente.org/) [7]
From: Brief comments on three existing approaches for managing neonates at risk of early-onset sepsis
Clinical Exam | Description |
|---|---|
Clinical Illness | 1. Persistent need for NCPAP / HFNC / mechanical ventilation (outside of the delivery room) 2. Hemodynamic instability requiring vasoactive drugs 3. Neonatal encephalopathy /Perinatal depression ▪ Seizure ▪ Apgar Score at 5 min < 5 4. Need for supplemental O2 > 2 h to maintain oxygen saturations > 90% (outside of the delivery room) |
Equivocal | 1. Persistent physiologic abnormality > 4 h ▪ Tachycardia (HR > 160) ▪ Tachypnea (RR > 60) ▪ Temperature instability (> 100.4 °F or < 97.5 °F) ▪ Respiratory distress (grunting, flaring, or retracting) not requiring supplemental O2 2. Two or more physiologic abnormalities lasting for > 2 h ▪ Tachycardia (HR > 160) ▪ Tachypnea (RR > 60) ▪ Temperature instability (> 100.4 °F or < 97.5 °F) ▪ Respiratory distress (grunting, flaring, or retracting) not requiring supplemental O2 Note: abnormality can be intermittent |
Well Appearing | No persistent physiologic abnormalities |