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Table 4 Intravenous treatment of non-complicated AHOM according to age

From: Italian consensus on the therapeutic management of uncomplicated acute hematogenous osteomyelitis in children

Age Empiric treatment (I choice) Empiric treatment (II choice)
<  3 months Ampicillin-sulbactam
OR
Cephazolin + Gentamycin
Oxacillin + Gentamycin
OR
Amoxicillin/clavulanate + Gentamycin
OR
Cefotaxime + Oxacillin
(if low prevalence of ESBL)
3 months- 5 years Cephazolin Amoxicillin/clavulanate
OR
Ampicillin/sulbactam
OR
Ceftriaxone
+
Clindamycin or Glycopeptides
(if MRSA prevalence > 10%)
>  5 years Oxacillin
OR
Cephazolin
OR
Clindamycin
Amoxicillin/clavulanate
OR
Ampicillin/sulbactam
OR
Ceftriaxone
OR
Ceftazidime
+
Clindamycin or Glycopeptides
(if MRSA prevalence > 10%)