Skip to main content

Table 5 Intravenous antibiotic dosage

From: Italian consensus on the therapeutic management of uncomplicated acute hematogenous osteomyelitis in children

Antibiotic Recommended dose
Amoxicillin/clavulanate 75–100 mg/kg daily of amoxicillin in 3–4 divided doses (max 1 g/dose)
Ampicillin/sulbactam 100–200 mg/kg daily of ampicillin in 4 divided doses (max 2 g/dose)
Cephazolin 150 mg/kg daily in 3–4 divided doses (max 2 g/dose)
Ceftazidime 150 mg/kg daily in 3 divided doses (max 2 g/dose)
Ceftriaxone 50–100 mg/kg daily (max 2 g)
Clindamycin 45 mg/kg daily in 3 divided doses (max 900 mg/dose)
Oxacillin 150–200 mg/kg daily in 4 divided doses (max 2 g/dose)
Gentamycin neonates ≥35 weeks of gestational age: 4 mg/kg daily during the first week of life, then 5 mg/kg daily
> 1 month-10 years: 8 mg/kg the first day, then 6 mg/kg daily
>  10 years: 7 mg/kg daily the first day, then 5 mg/kg daily
Linezolida <  12 years: 30 mg/kg daily in 3 divided doses (max 600 mg/dose)
> 12 years: 600 mg twice a day
Vancomycin 45 mg/kg daily in 3 divided doses
  1. aNot registered for pediatric use