Skip to main content

Table 5 Intravenous antibiotic dosage

From: Italian consensus on the therapeutic management of uncomplicated acute hematogenous osteomyelitis in children

Antibiotic

Recommended dose

Amoxicillin/clavulanate

75–100 mg/kg daily of amoxicillin in 3–4 divided doses (max 1 g/dose)

Ampicillin/sulbactam

100–200 mg/kg daily of ampicillin in 4 divided doses (max 2 g/dose)

Cephazolin

150 mg/kg daily in 3–4 divided doses (max 2 g/dose)

Ceftazidime

150 mg/kg daily in 3 divided doses (max 2 g/dose)

Ceftriaxone

50–100 mg/kg daily (max 2 g)

Clindamycin

45 mg/kg daily in 3 divided doses (max 900 mg/dose)

Oxacillin

150–200 mg/kg daily in 4 divided doses (max 2 g/dose)

Gentamycin

neonates ≥35 weeks of gestational age: 4 mg/kg daily during the first week of life, then 5 mg/kg daily

> 1 month-10 years: 8 mg/kg the first day, then 6 mg/kg daily

>  10 years: 7 mg/kg daily the first day, then 5 mg/kg daily

Linezolida

<  12 years: 30 mg/kg daily in 3 divided doses (max 600 mg/dose)

> 12 years: 600 mg twice a day

Vancomycin

45 mg/kg daily in 3 divided doses

  1. aNot registered for pediatric use