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Table 6 Suggested oral therapy in uncomplicated AHOM by age group

From: Italian consensus on the therapeutic management of uncomplicated acute hematogenous osteomyelitis in children

Age

Oral therapy

Unknown aetiological agent (age < 5 years)a

Cephalexin

OR

Amoxicillin-clavulanate +/− Rifampicin

Unknown aetiological agent (age > 5 years)

Cephalexin

OR

Flucloxacillin

OR

Clindamycin

S. aureus

Cephalexin

OR

Flucloxacillin

OR

Clindamycinb

OR

TMX-SMX + Rifampicinb

OR

Linezolidbc

K. kingae

Amoxicillin-clavulanate

OR

Cefixime

OR

Cefpodoxime

OR

Cefazolin

OR

Trimethoprim/sulphamethoxazole

S. pyogenes

Cephalexin

OR

Flucloxacillin

OR

Amoxicillin

  1. aOral antibiotic therapy is not indicated in infants < 3 months old
  2. bIf MRSA or PVL-SA is suspected or confirmed
  3. cNot registered for pediatric use