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Table 6 Relation of age, sex, and degree of thrombocytopenia with IL-17A genotypes

From: IL-23/Th17 pathway and IL-17A gene polymorphism in Egyptian children with immune thrombocytopenic purpura

Parameter

IL-17A Genotype

p-value

AA

AG

GG

N = 46

N = 10

N = 4

Age (years)

0.266

 Mean ± SD

6.7 ± 3.5

7 ± 3.7

11 ± 1.4

  (Range)

[2–12]

[1–10]

[10–12]

Sex

 Male

28 (60.9%)

6 (60.0%)

4 (100.0%)

0.820

 Female

18 (39.1%)

4 (40.0%)

0 (0.0%)

 

Thrombocytopenia

 Very severe

0 (0.0%)

2 (20.0%)

0 (0.0%)

 

 Severe

28 (60.9%)

8 (80.0%)

4 (100.0%)

0.380

 Moderate

12 (26.1%)

0 (0.0%)

0 (0.0%)

 

 Mild

6 (13.0%)

0 (0.0%)

0 (0.0%)

 
  1. N number, SD standard deviation