Table 1 Baseline characteristics of participants (n = 46)
ABE | No (n = 28) | Yes (n = 18) | P-value |
|---|---|---|---|
Demographic data | |||
Age, mean (SD), hours | 128.7 (94.2) | 174.2 (67.6) | 0.042 |
Gestational age, mean (SD), weeks | 38.8 (1.5) | 38.3 (0.9) | 0.205 |
Birth weight, mean (SD), kilogram | 3.28 (0.35) | 3.25 (0.45) | 0.825 |
Weight, mean (SD), kilogram | 3.14 (0.39) | 3.13 (0.41) | 0.923 |
Male, No. (%) | 13 (46.43%) | 11 (61.11%) | 0.331 |
Laboratory data | |||
TSB1, mean (SD), mg/dL | 25.96 (5.53) | 33.77 (5.94) | < 0.001 |
UB, mean (SD), mg/dL | 23.74 (5.12) | 30.35 (5.54) | < 0.001 |
TSB2, mean (SD), mg/dL | 11.13 (3.32) | 17.53 (6.27) | < 0.001 |
Blood glucose, mean (SD), mmol/L | 5.3 (1.2) | 6.9 (3.0) | 0.017 |
White blood cell, mean (SD), *10⋀9/L | 13.2 (5.1) | 14.2 (4.7) | 0.508 |
Blood platelet count, mean (SD), *10⋀9/L | 289.7 (125.6) | 264.0 (116.0) | 0.493 |
Red blood cell, mean (SD), *10⋀12/L | 4.07 (1.08) | 3.29 (0.72) | 0.010 |
Hemoglobin, mean (SD), g/L | 143.2 (35.5) | 116.1 (29.6) | 0.011 |
Serum sodium, mean (SD), mmol/L | 142.5 (3.0) | 142.1 (2.6) | 0.584 |
Serum calcium, mean (SD), mmol/L | 2.40 (0.25) | 2.38 (0.17) | 0.762 |
Serum potassium, mean (SD), mmol/L | 4.62 (0.52) | 4.39 (0.38) | 0.117 |
Serum albumin, mean (SD), g/L | 37.45 (2.80) | 36.12 (4.16) | 0.201 |
Acidosis, No. (%) | 5 (17.86%) | 6 (33.33%) | 0.230 |
Hypoxia, No. (%) | 1 (3.57%) | 2 (11.11%) | 0.552 |
Cause of severe hyperbilirubinemia | |||
Hemorrhage, No. (%) | 6 (21.43%) | 3 (16.67%) | 0.691 |
Hemolysis, No. (%) | 16 (57.14%) | 12 (66.67%) | 0.518 |
Infection, No. (%) | 11 (39.29%) | 8 (44.44%) | 0.729 |
Erythrocytosis, No. (%) | 2 (7.14%) | 0 (0.00%) | 0.246 |
Unknown reason, No. (%) | 1 (3.57%) | 3 (16.67%) | 0.124 |
Treatment | |||
Iv immunoglobulins, No. (%) | 6 (21.43%) | 7 (38.89%) | 0.199 |
Receive phototherapy before ET, No. (%) | 25 (89.29%) | 11 (61.11%) | 0.024 |