Skip to main content

Table 1 First-line therapies in pediatric eosinophilic esophagitis

From: Pediatric eosinophilic esophagitis: a review for the clinician

Drug

Daily induction dosing (usually divided doses)c

Proton pump inhibitors

 Omeprazole

1 mg/kg BID (max 20–40 mg)

 Lansoprazole

1 mg/kg BID (max 60 mg)

 Esomeprazole

1 mg/kg QD (max 40 mg)

 Pantoprazole

<  10 years of age: 1 mg/kg QD (max 40 mg)

> 10 years of age: 20 mg QD (max 40 mg)

Topical steroids

 Swallowed, inhaled fluticasone propionatea

88–440 μg BID-QID (max 880–1760 μg)

 Oral viscous budesonideb

<  10 years of age: 0.5 mg BID (max 4 mg)

> 10 years of age: 1 mg BID (max 4 mg)

Systemic steroids

 Prednisone

1–2 mg/kg BID (max 30 mg BID)

  1. a the patients should be instructed to puff the medication in the mouth during a breath-hold and not drink, eat or wash mouth for at least 30 min after swallowing
  2. b Budesonide orodispersible tablets are available in several European countries for adults only.
  3. c Specific doses in children will be determined by age, height or weight.
  4. Legend: BID Bis in die, two times a day, QD Quoque die, once a day, QID Quater in die, four times a day; max: maximum.