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Table 5 Multiple regression analysis for the BSID-III composite scores in preterm infants*

From: Altered microstructure of the splenium of corpus callosum is associated with neurodevelopmental impairment in preterm infants with necrotizing enterocolitis

BSID-III composite scores MD, sCC (10−3 mm2/s) GA PMA at MRI
Coefficient (SE) p value Coefficient (SE) p value Coefficient (SE) p value
Cognitive score −18.414 (10.791) 0.092 1.209 (0.580) 0.041 0.665 (0.842) 0.432
Language score −28.336 (12.402) 0.025 0.405 (0.667) 0.546 −0.131 (0.967) 0.892
Motor score −41.913 (13.254) 0.002 1.080 (0.713) 0.134 −0.425 (1.034) 0.682
  MD, ltCST (10−3mm2/s) GA PMA at MRI
Coefficient (SE) p value Coefficient (SE) p value Coefficient (SE) p value
Cognitive score −7.840 (15.431) 0.613 1.276 (0.591) 0.034 0.696 (0.870) 0.426
Language score −22.770 (17.840) 0.206 0.469 (0.683) 0.495 −0.198 (1.006) 0.845
Motor score −37.421 (19.380) 0.058 1.161 (0.742) 0.122 −0.564 (1.093) 0.608
  1. All regression analyses for each Bayley composite score included MD (sCC or ltCST), GA, and PMA at MRI scan
  2. Abbreviations: BSID-III Bayley Scales of Infant and Toddler Development-III, MD mean diffusivity, sCC corpus callosum splenium, GA gestational age, PMA postmenstrual age, SE standard error, ltCST left corticospinal tract, MRI magnetic resonance imaging
  3. *Includes 75 preterm infants (19 with NEC, 56 without NEC) out of 86 preterm infants