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Table 3 Main characteristics of immune responses in different patient groups [18]

From: Immune responses to alglucosidase in infantile Pompe disease: recommendations from an Italian pediatric expert panel

 

CN

CP HSAT

CP LT

Median time to seroconversion

4 weeks

4 weeks

8 weeks

Median titer at 26 weeks

1:51,200

1:51200

1:400

Median titer at 52 weeks

1:153,600

1:51,200

1:200

Median peak

1:204,800

1:204,800

1:800

  1. CN CRIM negative, CP CRIM positive, HSAT high sustained antibody titer, LT low titer