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Table 1 Groups of allergens related to the pathogenesis of HP in children

From: Pediatric hypersensitivity pneumonitis: literature update and proposal of a diagnostic algorithm

Environmental source class

Representative pathogens

Bacteria and mycobacteria

Thermophilic actinomycetes, Mycobacterium avium complex

Fungi

Aspergillus spp., Alternaria spp., Penicillium spp., Trichosporon spp.

Animal-derived proteins

Bird allergens, animal fur, cow’s milk

Plant proteins

Grain proteins, tea plants, coffee-bean dust

Chemicals

Plastics (e.g. isocyanates, anhydrides), detergents, pesticides (e.g. pyrethrum), e-cigarette liquids