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Table 2 Acute exacerbation of HP in children (modified from [39])

From: Pediatric hypersensitivity pneumonitis: literature update and proposal of a diagnostic algorithm

Criteria (>2 are needed for the definition of acute exacerbation) • Increase in respiratory rate > 20% from baseline
• Onset or increase of dyspnea
• Newly developing or increased abnormalities on chest imaging
• Onset/increase of oxygen demand to achieve baseline saturation (at rest and/or during exercise)
• Need for a supplementary level of ventilatory support (in addition to oxygen)
• Decrease in vital capacity at spirometry in children able to perform the tests (> 10%) from baseline
• Reduced exercise tolerance in children able to perform the tests (including desaturation)