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Fig. 1 | Italian Journal of Pediatrics

Fig. 1

From: L-alanine supplementation in Pompe disease (IOPD): a potential therapeutic implementation for patients on ERT? A case report

Fig. 1

Time-REE correlations with LAOS, patient on treatment vs. expected patient’s REE without intervention. Shapiro–Wilk normality test and repeated-Measures ANOVA were performed (with statistical significance p-value set at < 0.05) for studying the variables at each studied time with data grouped into two categories. First group contained the variables of basal metabolism repeated at 3 times of our patient (red line). Second group contained instead the expected basal metabolism variables without intervention, obtained with three different formulas* (Harris Benedict-REE; Schofield-REE; WHO-REE) at same three different times and based on patient’s parameters (black line). A statistically significant association can be found between intervention and time with the basal metabolism of our patient (p-value 0.004)

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