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Table 4 Neurodevelopmental outcomes, perinatal and socio-demographic characteristics of planned and unplanned infants (means, p-values)

From: Effect of medically assisted reproduction (MAR) and pregnancy planning on Bayley-III Screening Test subscales in preterm infants at 12 months of corrected age: a cross-sectional study

 

Mean subscale scores

p-values (test statistics)

 

Planned

(n = 149)

Unplanned (n = 17)

Mann–Whitney test

p-value (U)

t-test

p-value (t)

Neurodevelopmental outcomes

 Cognitive Subscale

16.95

16.17

0.027 (861.5)*

0.036 (2.109)*

 Receptive Language Subscale

11.63

10.17

0.001 (629.5)*

0.000 (3.623)*

 Expressive Language Subscale

10.93

10.05

0.015 (816.5)*

0.069 (1.830)

 Fine Motor Subscale

12.46

12.05

0.269 (1063.5)

0.312 (1.014)

 Gross Motor Subscale

15.46

14.52

0.089 (956.5)

0.044 (2.029)*

 

Perinatal and socio-demographic characteristics

p-values of t-tests or χ^2 tests

 

Perinatal data

 Gestational age (weeks), n (%)

  

0.892

 

  very early (< 28 weeks)

18 (12.08)

2 (11.76)

  

  early (28–31 weeks)

24 (16.10)

4 (23.52)

  

  moderate (32–33 weeks)

37 (24.83)

4 (23.52)

  

  late (34–36 weeks)

70 (46.97)

7 (41.17)

  

 Birth weight (g), n (%)

  

0.324

 

  LBW (1500–2499 g)

96 (64.42)

8 (47.05)

  

  VLBW (1000–1499 g)

31 (20.80)

6 (35.29)

  

  ELBW (< 1000 g)

22 (14.76)

3 (17.64)

  

 Mode of delivery, n (%)

  

0.497

 

  Sectio caesarea

102 (68.45)

13 (76.47)

  

  Per vias naturales

47 (31.54)

4 (23.52)

  

 Apgar scores, M ± SD

    

  1 min

7.68 ± 1.55

7.26 ± 2.18

0.340

 

  5 min

8.78 ± 1.11

8.73 ± 0.96

0.869

 

  10 min

9.25 ± 0.74

9.2 ± 0.63

0.839

 

 Intensive care

  

 

  NICU-admission, n (%)

125 (83.89)

15 (88.23)

  

  Sub-intensive care, n (%

16 (10.73)

1 (5.88)

  

 Chronic neonatal morbidities, n (%)

  BPD

12 (8.05)

0

 

  ROP

5 (3.35)

1 (5.88)

 

  IVH

5 (3.35)

0

 

  NEC

1 (0.67)

0

 

  PDA

11 (7.38)

1 (5.88)

 

  ASD

0

2 (11.76)

 

  VSD

1 (0.67)

1 (5.88)

 

Socio-demographic data

 Maternal age at childbirth (years), M ± SD

31.34 ± 5.71

26.94 ± 7.80

0.037*

 

 Maternal education, n (%)

  

0.159

 

  Primary

17 (11.40)

5 (29.41)

  

  Secondary technical education

21 (14.09)

4 (23.52)

  

  Secondary vocational education

23 (15.43)

3 (17.64)

  

  Secondary grammar education

17 (11.40)

2 (11.76)

  

  College

37 (24.83)

1 (5.88)

  

  University

32 (21.47)

1 (5.88)

  

 Marital status, n (%)

  

0.000*

 

  Single

3 (2.01)

4 (23.52)

  

  Married

101 (67.78)

4 (23.52)

  

  Cohabiting

33 (22.14)

6 (35.29)

  

  In a relationship

9 (6.04)

2 (11.76)

  

 Social status, n (%)

  

 

  Above-average

67 (44.96)

1 (5.88)

  

  Average

63 (42.28)

11 (64.70)

  

  Below-average

16 (10.73)

1 (5.88)

  
  1. * p < 0.05, in case of t-test either the independent sample one or the Welch statistic. Note that for some variables the joint frequencies are very low or equal to zero in several (too many) cells, hence the test and its p-value would not be meaningful in case of such an asymptotic test. In these cases (denoted by –) we omit to show the p-values