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Table 1 Demographical, anamnestic and clinical characteristics of patients with a new diagnosis of type 1 diabetes in the period 2019–2021

From: Increasing trend of type 1 diabetes incidence in the pediatric population of the Calabria region in 2019–2021

  2019 2020 2021 2019–2021
Number of T1D diagnosis 43 53 58 154
Age at diagnosis (years) 8.9 (5.8; 12.2) 8 (3.3; 10.7) 8.3 (4.5; 11) 8.9 (5.2; 12.1)
Gender
 Male 18 (41.9%) 27 (50.9%) 24 (41.4%) 69 (44.8%)
 Female 25 (58.1%) 26 (49.1%) 34 (58.6%) 85 (55.2%)
BMI (z-score) 0.63 (-0.91; 1.71) 0.25 (-1.04; 1.2) 0.1 (-1.24; 0.79) 0.2 (-1.07; 1.2)
HbA1c at diagnosis (%) 11.4 (9.8; 13.1) 11.7 (10.4; 13.3) 11.9 (10.5;13.4) 11.6 (10.1; 13.4)
DKA
 Yes 19 (44.1%) 27 (50.9%) 25 (43.1%) 71 (46.1%)
 No 24 (55.9%) 26 (49.1%) 33 (56.9%) 83 (53.9%)
Severity DKA
 Mild 7 (36.8%) 11 (40.7%) 11 (44%) 29 (41%)
 Moderate 4 (21.1%) 4 (26.9%) 6 (24%) 14 (19.7%)
 Severe 8 (42.1%) 12 (44.4%) 8 (32%) 28 (39.3%)
DKA-related complications
 Yes 0 0 0 0
 No 43 (100%) 53 (100%) 58 (100%) 154 (100%)
T1D autoimmunity
 Yes 38 (88.4%) 47 (88.7%) 56 (96.6%) 141 (91.6%)
 No 5 (11.6%) 6 (11.3%) 2 (3.4%) 13 (8.4%)
Other autoimmune disorders
 Yes 5 (11.6%) 8 (15.1%) 5 (8.6%) 18 (11.7%)
 No 38 (88.4%) 45 (84.9%) 53 (91.4%) 137 (88.3%)
T1D in first-degree relatives
 Yes 3 (7.0%) 3 (5.7%) 3 (5.2%) 9 (5.8%)
 No 40 (93.0%) 50 (94.3%) 55 (94.8%) 145 (94.2%)
  1. BMI Body Mass Index, DKA Diabetic Ketoacidosis, T1D Type 1 Diabetes