Narrative review on the management of moderate-severe atopic dermatitis in pediatric age of the Italian Society of Pediatric Allergology and Immunology (SIAIP), of the Italian Society of Pediatric Dermatology (SIDerP) and of the Italian Society of Pediatrics (SIP)

Table 8 Dupilumab in adolescents with moderate to severe dermatitis

Main clinical trials
Phase 2 open-label study R 668-AD1412
Pharmacokinetics, safety, efficacy in patients aged 6 to 17 years
Liberty ADOL
Phase 3 pilot monotherapy study R 668-AD 1526
Safety and efficacy in patients aged 12 to 17 years
Liberty AD PED OLE
Phase 3 study Open-Label Extension (OLE) R 668-AD 1434
Safety and efficacy in patients 6 months to <18 years

ISSN: 1824-7288