Narrative review on the management of moderate-severe atopic dermatitis in pediatric age of the Italian Society of Pediatric Allergology and Immunology (SIAIP), of the Italian Society of Pediatric Dermatology (SIDerP) and of the Italian Society of Pediatrics (SIP)

Table 9 Recommended dose of dupulumab for the treatment of pediatric atopic dermatitis

Adolescents between the ages of 12 and 17
Bodyweight	Starting dose	Subsequent doses
Less than 60 kg	400 mg (two 200 mg injections)	200 mg every 2 weeks
60 kg or more	600 mg (two 300 mg injections)	300 mg every 2 weeks
Children between the ages of 6 and 11
Bodyweight	Starting dose	Subsequent doses
15 to less than 60 kg	300 mg (one 300 mg injection) on day 1, followed by 300 mg on day 15	300 mg every 4 weeks^a, starting 4 weeks after the day 15 dose
60 kg or more	600 mg (two 300 mg injections)	300 mg every 2 weeks

^aThe dose may be increased to 200 mg every 2 weeks in patients weighing 15 kg to less than 60 kg based on the physician's assessment

ISSN: 1824-7288