Table 1 Clinical characteristics of the pediatric patients with invasive aspergillosis in Shiraz, southern Iran

Demographic features

 Male/female (%)

39/34 (53.4%/46.6%)

 Age mean (range)

5 years (10 month > 18 years)

Underlying Disease

 Hematologic disorders

52 (71.2%)

 Heart surgery

8 (11%)

 Liver Surgery

6 (8.2%)

 Immunodeficiency disease

5 (6.8%)

 AIDS

1 (1.4%)

 Diabetes

1(1.4%)

Site of infection

 Lung

38 (52%)

 Liver

24 (32.9%)

 Heart

7 (9.6%)

 Sinuses

5 (6.8%)

 Kidney

2 (2.7%)

 Fever of unknown origin

9 (12.3%)

Antifungal therapy

 Not used

30 (41.1%)

 Amphotericin B

9 (12.3%)

 Itraconazole

4 (5.5%)

 Voriconazole

3 (4.1%)

 Fluconazole

8 (11%)

 Combination therapy^a

19 (26%)

Outcome

 Alive

53 (72.6%)

 Death

20 (27.4%)