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Table 3 Prevalence of auxological, clinical, pathologic features and therapy in children with DS

From: Diencephalic syndrome in childhood, a challenging cause of failure to thrive: miniseries and literature review

Auxological parameters

(percentile)

%

Clinical features

%

Pathology

%

Therapy

%

Outcome

%

W < 5th

80

Nystagmus

43

Astrocytoma

83

Chemotherapy

49

Survivor

72.5

W/L or W/H or BMI < 5th

96

Vomiting

35

Craniopharyngioma

12.5

Radiotherapy

47

died

24.5

HC > 97th

25

Hyperactivity/happiness

26

  

Total resection

17

  

L or H < 5th

4

Visual loss

26

  

Partial resection

44

  

L or H > 97th

4

Strabismus

15

      
  

Irritability

8

      
  

Headache

8

      
  

Neurodevelopment delay

7

      
  

Anorexia

6

      
  

Lethargy

5

      
  

Papilledema

3

      
  

Seizures

2

      
  1. W Weight, L Length, H Height, W/L Weight/Length, W/H Weight/Height, BMI Body mass index, HC head circumference