Table 3 The value of ADA in children with positive plasma EBV-DNA
From: Diversity of adenosine deaminase in children with EBV-related diseases
Diseases | Normal ALT | Elevated ALT | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
N = 483 | n = 279 | Gender (male) | ADA [U/L,M(P25,P75)] | ADA↑ n(%) | n = 204 | Gender (male) | ADA [U/L,M(P25,P75)] | ADA↑ n(%) | ALT [U/L,M(P25,P75)] | |
Respiratory infection | 131 | 107 | 62 (57.9) | 23.8 (19.3-35.0)a | 49 (45.8)a | 24 | 17 (70.8) | 51.6 (41.2-60.1)ac | 22 (91.7)a,b | 57.9 (43.6-111.7)a |
IM | 161 | 73 | 46 (63.0) | 47.2 (40.4-59.1)b | 71 (97.3)b | 88 | 42 (47.7) | 65.9 (54.2-77.4)b | 88 (100.0)b | 77.9 (49.8-119.7)ab |
Atypical EBV infection | 96 | 36 | 23 (63.9) | 45.9 (37.1-53.2)b | 33 (91.7)b | 60 | 33 (55.0) | 55.4 (48.6-72.4)ab | 56 (93.3)a,b | 102.2 (74.2-162.8)b |
Malignant disease | 50 | 28 | 13 (46.4) | 25.6 (13.0-44.3)a | 16 (57.1)a | 22 | 12 (54.5) | 28.3 (12.9-47.5)c | 12 (54.5)c | 65.5 (51.7-110.7)ab |
Other diseases | 45 | 35 | 19 (54.3) | 25.5 (17.0-40.3)a | 18 (51.4)a | 10 | 6 (60.0) | 40.2 (20.7-71.1)abc | 7 (70.0)a,c | 65.3 (46.9-140.3)ab |
P | 0.559 | < 0.001 | < 0.001 | 0.367 | < 0.001 | < 0.001 | < 0.001 |